Denosumab for preventing fractures in people with type 2 diabetes
Part of Bones, joints & muscles, Hormones & metabolism, Injuries & trauma clinical trials.
This study tests whether denosumab, a medication given as an injection, can help prevent broken bones in people with type 2 diabetes who are at high risk for fractures. It aims to see if this treatment can strengthen bones and reduce fracture risk.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have type 2 diabetes.
- Women must be at least 45 years old and past menopause for over 2 years; men must be at least 50.
- You must have had diabetes for more than 10 years, or have certain diabetes-related complications (like eye, kidney, heart, or blood vessel problems).
- Your blood sugar control (HbA1c) must be 8.0% or lower, measured within the last month.
- You must have had a broken bone (fracture) in your hip or spine, or have low bone density (T-score) at certain sites.
- You must not have taken certain osteoporosis medications recently (like bisphosphonates, denosumab, teriparatide, or romosozumab).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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