Skin vs cheek graft for urethra repair
Part of Kidney & urinary, Women’s health & pregnancy clinical trials.
This trial compares using skin from your penis versus tissue from inside your cheek to fix a long, tight scar in the front portion of your urinary tube (urethra). It may help if you have this scar and past attempts to widen the tube have failed.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a scar longer than 1 cm in the front part of your urethra that has damaged the tissue around it.
- You must have had past procedures like stretching or cutting inside the urethra that did not work.
- You cannot have a skin condition called lichen sclerosus.
- You cannot have had prior surgery to fix hypospadias (a birth defect where the pee hole is on the underside of the penis).
- You cannot have had a previous urethra repair that failed.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new surgical method to repair a nearly closed bulbar urethral stricture (a narrowed part of the urine tube in the penis). This special technique uses tissue from the inside of your cheek to widen the tight spot.
This trial compares using a graft from the mouth or lip to treat a narrowed urethra in women. It aims to find which approach works better for improving urinary flow.
This trial compares general anesthesia versus spinal anesthesia with local numbing medicine for penis skin graft surgery. It aims to see which method works better for pain control and recovery.
This study compares doing a graft in the first versus the second step of a two-stage urethral repair in men with a penile urethral narrowing. It uses oral lining tissue as the graft and aims to see which timing approach works best for healing and function.
This early study tests whether an engineered urethral patch made from your own body tissue is safe and workable for urethral strictures (narrowing that blocks urine flow). It is mainly looking for safety and how feasible the procedure and follow-up are, not proven cure yet.
This study compares two surgical techniques to repair a short (2 cm or less) narrowing in the bulbar urethra. It aims to see which method works better for men with non-traumatic strictures.
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