Clin2
NCT07077356Possibly a fitRecruiting

mRNA vaccine for liver cancer patients awaiting transplant

Hepatocellular Carcinoma (HCC)

Part of Cancer, Digestive system clinical trials.

This trial tests an mRNA vaccine for people with liver cancer who are waiting for a liver transplant. The vaccine is given to help control the cancer while they wait.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
15 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older
  • You have hepatocellular carcinoma (liver cancer) that meets the criteria for a liver transplant
  • You are waiting for a liver transplant and need treatment to control the cancer during the wait
  • You are positive for hepatitis B (HBsAg)
  • You are able to carry out daily activities with little to no help (ECOG score 0-2)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07495215Recruiting· Phase 1/Phase 2
Personalized mRNA vaccine plus immunotherapy for liver cancer after surgery

This trial tests a personalized mRNA vaccine (iNeo-Vac-R01) combined with a PD-1 inhibitor to prevent liver cancer from coming back after surgery. It is for people with early-stage liver cancer who have a high risk of recurrence.

Hangzhou, Zhejiang
NCT07324304Recruiting· Phase 2
DNA vaccine for liver cancer after curative surgery

This trial tests a DNA-based vaccine called NWRD06 to lower the risk of liver cancer returning after a curative surgery or ablation. It is for people with a specific protein on their cancer cells and good liver function.

Beijing, Beijing Municipality
NCT07120750Not yet recruiting
Antiviral treatment after liver cancer surgery

This trial tests whether continuing antiviral therapy after surgery for hepatitis B-related liver cancer can improve outcomes. It focuses on patients with early-stage disease, good liver function, and no prior cancer treatments other than surgery or ablation.

NCT07053072Recruiting· Phase 1
PD-1 mRNA vaccine for advanced liver cancer

This trial tests a new mRNA vaccine for people with advanced liver cancer that has returned or spread after other treatments. The vaccine aims to help your immune system fight the cancer more effectively.

Chengdu, Sichuan
NCT06995105Recruiting· Phase 1/Phase 2
Personalized mRNA Vaccine for Advanced Liver Cancer

This trial tests a personalized mRNA vaccine made from your tumor's unique genetic markers. It is for people with advanced liver cancer who have not yet received any treatment.

Hangzhou, Zhejiang
NCT04745403Recruiting· Phase 1
Trial of redirected HBV-targeting T cells for liver cancer

This Phase 1 study tests a lab-made immune cell treatment that targets hepatitis B (HBV)–related liver cancer. It may help by directing the body’s immune system to attack the cancer, while carefully checking safety.

Singapore

Hear when a new Hepatocellular Carcinoma (HCC) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.