Can a blood test replace bone marrow biopsy for low blood counts?
Part of Blood & lymphatic clinical trials.
This study tries to see if blood tests can replace a bone marrow biopsy for people with low blood counts (cytopenia) and suspected MDS (myelodysplastic syndrome). It aims to make diagnosis less invasive by using a simple blood draw instead of a bone marrow sample.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have low blood counts (low platelets, low white blood cells, or low hemoglobin).
- Your low counts are NOT caused by low iron, folate, or vitamin B12.
- You do NOT have a past diagnosis of leukemia, lymphoma, or similar blood cancers.
- You have not had a bone marrow transplant.
- You are not currently receiving specific treatments for your blood condition (except some like erythropoietin).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study follows people who may have early, unclear blood count problems or certain genetic/immune patterns that can later lead to bone marrow failure or blood cancers. It may help doctors better understand risks over time and guide earlier care.
This trial tests elritercept, a medicine meant to improve anemia (low blood count) in adults with certain lower-risk bone marrow disorders called MDS. If you qualify, the study may help reduce the need for blood transfusions or improve anemia symptoms.
This study tests a new drug called elritercept for people with myelodysplastic syndromes (MDS) who have low blood counts and need regular blood transfusions. The drug aims to boost red blood cell production and reduce or eliminate the need for transfusions, which can improve energy and quality of life.
This study looks at whether a simple blood test can give the same information as a bone marrow biopsy for people with myeloproliferative neoplasms (MPNs), which are blood cancers that cause the bone marrow to make too many cells. If successful, it could mean less invasive testing for patients.
This study looks at the causes of pancytopenia, a condition where all three types of blood cells (red, white, and platelets) are lower than normal. By doing blood tests and a bone marrow biopsy, doctors hope to better understand what is causing it and improve care.
This study follows people with ongoing low blood counts (red cells, white cells, and/or platelets) to better understand their condition when it does not meet criteria for MDS. It may help improve how persistent blood count problems are evaluated over time.
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