Clin2
NCT07082803Possibly a fitRecruiting

TLN-121 for relapsed or refractory lymphoma

LymphomaLymphoma, Non Hodgkin

Treatments studied

Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.

This trial tests an investigational drug (TLN-121) for people with certain types of lymphoma that have come back or stopped responding to previous treatments. It aims to see if the drug can control the cancer and how safe it is.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
180 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must have measurable disease (tumor that can be measured).
  • Diagnosis must be one of the specified lymphoma types (e.g., DLBCL, FL grade 3b, transformed FL, or certain T-cell lymphomas).
  • Must have received at least 2 prior lines of therapy (or at least 1 for certain T-cell types).
  • Must have good performance status (ECOG 0 or 1).
  • No current CNS involvement; if past CNS disease, must be fully treated and recurrence-free for 12 months.
  • No stem cell transplant within the last 60 days (autologous) or 90 days (allogeneic).
  • No CAR-T or other T-cell therapy within the last 4 weeks.
  • No major surgery or severe trauma within the last 4 weeks.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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