Clin2
NCT07084831Possibly a fitNot yet recruiting

Effect of an experimental medication on thinking and memory in schizophrenia

Schizophrenia; PsychosisCognitive Impairment

Part of Mental health clinical trials.

This study tests a new combination medication (xanomeline/trospium) to see if it helps improve thinking and memory problems in people with schizophrenia. It lasts about a year, and participants continue their usual antipsychotic treatment.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
171 people
Ages
18 years to 55 years
Study type
Interventional

Who can take part

  • Be between 18 and 55 years old
  • Have a diagnosis of schizophrenia (confirmed by a doctor)
  • Currently on a stable dose of an oral antipsychotic medication for at least 4 weeks
  • Have some cognitive (thinking) difficulties, as measured by a short test
  • Not be pregnant, breastfeeding, or at high risk for suicide
  • Not have certain health conditions (like significant kidney, liver, or bladder problems)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06923891Not yet recruiting· Phase 4
A study of xanomeline/trospium for early schizophrenia

This study tests a new combination medication (xanomeline/trospium) for people with early schizophrenia who want to switch antipsychotics. The goal is to see if it helps control symptoms and is easier to tolerate.

Richmond, Texas
NCT06924255Not yet recruiting· Phase 4
Switching Antipsychotic Medications for Schizophrenia

This study tests two ways of switching from your current antipsychotic to a new combination medication (xanomeline and trospium). The goal is to see which approach is safer and easier for people with schizophrenia.

Bellflower, California
NCT07101094Recruiting
Study on satisfaction with a new schizophrenia treatment

This study tracks how satisfied people with schizophrenia are with a new combination medicine called xanomeline and trospium chloride (XT). It aims to understand real-world experiences and benefits of this treatment.

Orange, California
NCT07686263Recruiting· Phase 3
Testing a new drug to prevent schizophrenia relapse

This trial tests whether a new oral medication, KarXT, can help prevent a return of schizophrenia symptoms in people who have been stable on treatment. If you've had a hospital stay in the past year and still have some symptoms, you may be able to join.

Bentonville, Arkansas
NCT06021197Recruiting· Phase 2
NMDA-enhancing treatment for cognitive symptoms in schizophrenia

This study tests a new treatment that may help with thinking and memory problems in people with schizophrenia. It is for people whose schizophrenia symptoms are stable and who are already on a steady medication.

Taichung
NCT07191483Recruiting· Phase 2
Study of KYN-5356 for cognitive problems in schizophrenia

This trial tests an investigational drug, KYN-5356, to see if it can improve thinking and memory problems in adults with schizophrenia. You may join if your schizophrenia is stable and you take only one antipsychotic medication.

Little Rock, Arkansas

Hear when a new Schizophrenia; Psychosis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.