Clin2
NCT07085091Possibly a fitRecruiting

Study of ALX2004 for advanced solid tumors

NSCLC (Advanced Non-small Cell Lung Cancer)HNSCCCRC (Colorectal Cancer)ESCCColo-rectal CancerHead and Neck CancerEsophageal Squamous Cell Carcinoma (ESCC)

Part of Cancer, Digestive system, Lungs & breathing clinical trials.

This trial tests a new drug, ALX2004, for people with certain advanced cancers (head and neck, lung, esophagus, or colorectal) that have stopped responding to standard treatments. The goal is to see if the drug is safe and effective.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
170 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have one of these cancers: head and neck, lung, esophagus, or colorectal cancer, and it has spread or come back and cannot be surgically removed.
  • Your cancer has gotten worse after at least one prior treatment, and no standard therapy is available for your situation.
  • For certain cancer types, you have had a limited number of prior treatments (e.g., no more than 2-4 lines of therapy depending on your cancer).
  • You are in generally good health, with adequate blood cell counts, kidney and liver function, and ability to perform daily activities.
  • You have not had a prior ADC (antibody-drug conjugate) that targets TOP1 (a specific enzyme).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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