Nano megestrol for appetite and weight loss in advanced lung cancer
Treatments studied
Part of Cancer, Lungs & breathing clinical trials.
This trial tests a nano form of megestrol acetate, a drug that may help improve appetite and reduce weight loss in people with advanced lung cancer who have already lost weight or have signs of inflammation. It's for those who have not yet had chemotherapy for advanced disease.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have stage 3C or 4 non-small cell lung cancer or extensive-stage small cell lung cancer.
- You have not had chemotherapy for advanced lung cancer, or if you had chemo or radiation to try to cure cancer, it has been over 6 months since that treatment ended.
- You have lost weight without trying (up to 5% in the last 6 months with inflammation, or more than 5% in 6 months, or more than 2% if your BMI is below 18.5).
- You have a decreased appetite, based on a quiz (FAACT score 37 or less).
- You are between 18 and 75 years old and feel well enough to do daily activities (ECOG 0-2).
- You are not taking other appetite-stimulating medications or have serious stomach or intestinal problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a medicine called nanocrystalline megestrol acetate to help people with advanced small cell lung cancer who have lost weight and appetite. The goal is to see if the drug can improve their condition.
This trial tests whether a medicine called megestrol acetate can help improve appetite and weight in people with advanced lung cancer who are malnourished. It's for those who haven't had chemotherapy for their advanced cancer yet.
This trial tests a new form of megestrol acetate (a medicine used to boost appetite and help with weight gain) in people with advanced lung cancer who are losing weight or at risk of weight loss. It aims to improve appetite and help you gain weight.
This trial tests if a new form of megestrol (a medicine that can increase appetite) helps people with advanced lung cancer who are losing weight. It is for patients who have not yet received chemotherapy for their cancer and are at risk of malnutrition.
This trial tests a new appetite-boosting medicine (nano-crystalline megestrol acetate) added to standard chemotherapy for people with advanced small cell lung cancer who are losing weight. It aims to see if it helps with weight, strength, and treatment response.
This trial tests a new form of a drug (nano-megestrol acetate) to help people with advanced pancreatic cancer who are losing weight and have poor appetite. It aims to see if it can improve cachexia, a condition of severe weight loss and muscle wasting.
Hear when a new Lung cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.