Daily enzyme therapy for infected pleural fluid
Part of Infections, Lungs & breathing clinical trials.
This trial tests a once-daily enzyme treatment given through a chest tube to clear infected fluid from around the lungs. It may help people with complicated pneumonia or empyema who still have fluid buildup after initial drainage.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older
- You must be hospitalized with a chest tube draining infected fluid from around your lung
- Your pleural fluid must be pus-like, have bacteria, or meet lab criteria (low pH, low glucose, or high LDH)
- You must still have fluid or signs of infection 24 hours after your chest tube was placed
- You cannot have had a stroke, major bleeding, trauma, or major surgery in the last 5 days
- You cannot be on blood thinners that can't be stopped for 48 hours before treatment
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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