Oral artesunate for cervical precancer
Treatments studied
Part of Cancer clinical trials.
This trial tests an oral medication called artesunate to see if it can help treat cervical precancer (CIN2/3) caused by HPV. It is a possible option for women who are newly diagnosed and have not had this condition before.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must have a confirmed diagnosis of CIN2 or CIN3 that is related to HPV.
- You must be in generally good health (able to do daily activities without major help).
- You must have adequate blood counts (kidney and liver function tests will be checked).
- If you could become pregnant, you need a negative pregnancy test and must use reliable birth control during the study and for 6 weeks after.
- You cannot have had CIN before, be pregnant or breastfeeding, weigh less than 52 kg, or have a weakened immune system.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This Phase 2 study tests whether artesunate vaginal inserts can help treat high-grade abnormal cells on the cervix (CIN2/3). It’s meant for adults who have a confirmed high-grade precancer change and can use birth control during the study.
This trial tests an artesunate ointment to treat high-grade anal precancer (HSIL) in people who do not have HIV. The goal is to see if the ointment can clear the abnormal cells caused by HPV.
This trial tests an artesunate ointment for women with high-grade vulvar lesions caused by HPV. It aims to see if the ointment can help the lesions heal or disappear without needing surgery.
This study tests a new method using low-temperature argon plasma to treat cervical precancer (CIN 2) and compares it with the standard approach of active surveillance. If you have CIN 2 and are between 18 and 40 years old, this trial may offer an alternative to watching and waiting.
This study tests a light-based treatment (photodynamic therapy) for cervical precancer called CIN2. It may be an option if you want to avoid surgery and preserve the cervix.
This Phase 2 study tests whether a curcumin (a natural plant compound) cream/gel applied to the cervix can help treat cervical cell changes linked to HPV. It focuses on people with mild (LSIL) or recently treated severe (HSIL) precancer changes, aiming to reduce disease and improve healing.
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