Clin2
NCT07109219Possibly a fitRecruiting

Study of AZD4512 alone or with other drugs for leukemia

B-cell Acute Lymphoblastic Leukemia (B-ALL)

Part of Blood & lymphatic, Cancer, Immune system & allergy, Infections clinical trials.

This study tests a new medicine called AZD4512, given alone or with other cancer drugs, for people whose B-cell acute lymphoblastic leukemia (a type of blood cancer) has come back or not improved after treatment. The goal is to see if it can help control the disease.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
83 people
Ages
12 years and older
Study type
Interventional

Who can take part

  • You are a teenager (at least 12 or 16 years old, depending on the study part).
  • You have B-cell acute lymphoblastic leukemia (B-ALL) that is CD22-positive and has relapsed (returned) or is refractory (did not respond to treatment).
  • You have received at least one or two prior treatments, depending on the study part, and the disease did not respond or came back.
  • You are in reasonably good health (able to carry on daily activities) and your blast count (a type of white blood cell) is below a certain level.
  • You have waited long enough after previous treatments, such as stem cell transplants or certain drugs, before joining this study.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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