Desloratadine to prevent nerve damage from taxane chemo in breast cancer
Part of Brain & nervous system, Cancer, Skin clinical trials.
This trial tests if the allergy medicine desloratadine can prevent nerve damage (numbness, tingling, pain) caused by taxane chemotherapy in people with early-stage breast cancer. Taking desloratadine daily during chemo may help protect your nerves.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have breast cancer that is stage I, II, or III (not spread to other organs).
- You are scheduled to receive a taxane chemotherapy (like paclitaxel or docetaxel) for at least 12 weeks, often before or after surgery.
- You have never had nerve damage (peripheral neuropathy) or taken a taxane or platinum chemo before.
- You are not currently taking any allergy medicines (antihistamines), probiotics, laxatives, or antibiotics (within the last 4 weeks).
- If you could become pregnant, you must have a negative pregnancy test and use effective birth control during and for 28 days after treatment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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