Clin2
NCT07128355Possibly a fitRecruiting

Combined immunotherapy and radiation for colorectal cancer

Non-MSI-H or pMMR Colorectal Cancer With Liver Metastasis

Treatments studied

Part of Cancer, Digestive system clinical trials.

This trial tests the combination of two immunotherapy drugs (botensilimab and balstilimab) plus targeted radiation to liver tumors. It's for people with colorectal cancer that has spread and hasn't responded to standard treatments.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
15 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have colorectal cancer that has spread to the liver and at least one other spot outside the liver
  • Your cancer is mismatch repair stable (MSS) or has normal MMR function
  • You've tried or can't take 5-FU, oxaliplatin, and irinotecan
  • You're 18 or older and in fairly good health (ECOG 0 or 1)
  • You have no active autoimmune disease or serious bowel obstruction
  • You're not pregnant and agree to use effective birth control

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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