Clin2
NCT07129031Possibly a fitNot yet recruiting

Blood transfusion strategies for severe bleeding

HemorrhageHemorrhagic ShockUpper Gastrointestinal Bleeding (UGIB)

Part of Digestive system clinical trials.

This study is testing different ways to use blood transfusions in emergency situations to improve survival and recovery for people with severe bleeding from injury or stomach/intestinal bleeding. The goal is to find the best transfusion approach to help patients like you.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
180 people
Ages
10 years to 90 years
Study type
Interventional

Who can take part

  • You must be between 10 and 90 years old.
  • You must have severe bleeding caused by an injury or from the upper part of the digestive system (stomach or esophagus).
  • Your bleeding must be rapid enough that you need emergency blood transfusion (hemoglobin below 7 g/dL or actively bleeding).
  • You need to arrive at the hospital within 24 hours of the bleeding starting.
  • You cannot have end-stage organ failure, active cancer, a bleeding disorder, or a history of severe transfusion reactions.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06070350Recruiting· Phase 3
Massive transfusion for life-threatening bleeding in children

This study tests whether adding the drug tranexamic acid (TXA) to a massive blood transfusion helps control life-threatening bleeding in children who are severely injured. It compares two groups: one gets TXA and the other gets a placebo (a dummy drug with no active ingredient).

Tucson, Arizona
NCT07695129Not yet recruiting
Managing blood loss from broken leg, arm, or hip bones

This study looks at how well the body handles blood loss after a serious bone break, like a broken thigh, shin, or hip. It may help doctors understand the best way to treat people who have lost blood from these injuries.

Sohag
NCT05634109Recruiting· Phase 3
Whole blood to treat adults with severe bleeding trauma

This trial compares giving whole blood versus standard care in adults with severe trauma and dangerous blood loss (hemorrhagic shock). The goal is to see if whole blood helps stabilize patients faster and improves outcomes after major bleeding.

Cali, Valle del Cauca Department
NCT06891131Recruiting
Blood transfusion bundle for severe bleeding after injury

This trial tests a standard set of emergency blood transfusions for people with life-threatening bleeding from a serious injury. It aims to improve survival by giving blood products quickly before reaching the hospital.

Graz
NCT06019364Enrolling by invitation
Whole Blood Transfusion for Acute Bleeding

This trial looks at people who received whole blood transfusions during a sudden, heavy bleeding episode. It aims to learn more about how well whole blood works in these situations.

Örebro
NCT07748663Not yet recruiting
Blood transfusion strategies during major surgery

This study compares two different blood transfusion strategies during major surgery to see which is safer and more effective. If you are having major surgery and might need a blood transfusion, this trial could help guide how your doctors manage your blood levels.

Ottawa, Ontario

Hear when a new Hemorrhage trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.