Massive transfusion for life-threatening bleeding in children
Treatments studied
Part of Injuries & trauma clinical trials.
This study tests whether adding the drug tranexamic acid (TXA) to a massive blood transfusion helps control life-threatening bleeding in children who are severely injured. It compares two groups: one gets TXA and the other gets a placebo (a dummy drug with no active ingredient).
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your child must be under 18 years old and have a serious traumatic injury.
- The hospital has activated a 'massive transfusion protocol' because your child has or is suspected to have severe, life-threatening bleeding.
- Your child must have at least 2 out of 3 signs of severe bleeding: low blood pressure, very fast heartbeat, or clear signs of a serious injury.
- Your child does not have a devastating brain injury that doctors believe is not survivable.
- Your child has not already received another study drug or been enrolled in this trial before.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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