Metformin to lower risk of severe morning sickness
Part of Women’s health & pregnancy clinical trials.
This trial tests if taking metformin before pregnancy can reduce the chance of severe morning sickness (hyperemesis gravidarum) in women who had it before. You would take a daily pill and be followed closely.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 49 years old
- You had severe morning sickness in a past pregnancy that required IV fluids
- You are trying to get pregnant now
- You have a regular menstrual cycle
- You live in California or Alabama (treatment arm) or anywhere for the survey/comparison group
- You do not take any of these daily: tobacco, certain muscle relaxants, cannabis, or some antidepressants
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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