Clin2
NCT06445946Possibly a fitRecruiting

Metformin vs insulin for gestational diabetes

Gestational Diabetes MellitusPregnancy, High Risk

Treatments studied

Part of Hormones & metabolism, Women’s health & pregnancy clinical trials.

This study compares two common medicines (metformin pills and insulin shots) to see which works better for controlling blood sugar in pregnant women with gestational diabetes. The goal is to find the best treatment for both mom and baby, now and in the long term.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
1,572 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are pregnant with one baby (not twins or more).
  • You are 18 years or older.
  • You are between 20 and 33 weeks pregnant.
  • Your gestational diabetes requires medication to manage blood sugar levels.
  • You are willing to attend a follow-up visit 2 years after your baby is born.
  • You do not have kidney disease or a known allergy to metformin or insulin.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05124808Recruiting
Tight blood sugar targets in pregnant women with gestational diabetes

This study compares a tighter blood sugar goal versus a standard goal in pregnant people with gestational diabetes who are also overweight or obese. It may help find whether stricter blood sugar control improves pregnancy outcomes.

Birmingham, Alabama
NCT07806695Recruiting· Phase 1
Understanding insulin production in gestational diabetes

This study looks at how the body makes insulin during pregnancy to understand why some women get gestational diabetes. If you join, you'll have some extra blood tests during pregnancy and after birth to help researchers learn more.

Rochester, Minnesota
NCT06781775Recruiting· Phase 4
Metformin vs insulin for gestational diabetes

This trial compares two medicines—metformin pills and insulin shots—to see which works better for controlling blood sugar in gestational diabetes. You may be able to join if you have gestational diabetes that needs treatment and are willing to take either medicine.

Charlottesville, Virginia
NCT07802561Recruiting· Phase 4
Metformin vs glyburide for gestational diabetes

This study compares two medicines, metformin and glyburide, to see which is better at controlling blood sugar in pregnant women with gestational diabetes. If you need medication to manage your blood sugar during pregnancy, this trial might help guide treatment choices.

Multan, Punjab Province
NCT02947503Recruiting· Phase 3
Metformin for gestational diabetes in pregnancy outcomes

This study tests whether taking metformin during pregnancy improves outcomes for people with gestational diabetes. It may help with pregnancy health and baby outcomes compared with the study’s other diabetes care plan.

Groningen
NCT06840613Not yet recruiting
Comparing two treatments for blood sugar control in gestational diabetes

This trial compares two treatments for gestational diabetes: metformin alone versus metformin combined with myo-inositol. It aims to find out if the combination helps manage blood sugar better during pregnancy.

Hear when a new Pregnancy, High Risk trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.