Monitoring immune response in severe abdominal infections with fungal risk
Part of Infections clinical trials.
This trial monitors a marker of immune function (monocyte HLA-DR) in patients with severe abdominal infections that may lead to fungal infections. It aims to see if this marker can help guide treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must be in the ICU or a step-down unit for a severe abdominal infection that needed urgent surgery.
- You must have at least one risk factor for fungal infection in the abdomen, such as recent surgery, a perforated bowel, or being on strong antibiotics before surgery.
- You must not have a planned surgery without an incision (drainage with a needle) for your infection.
- You must not have a severe case of pancreatitis that is infected.
- You must not be in a situation where life-sustaining treatments are being stopped or withdrawn.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial looks at natural molecules that help the body resolve severe infections. Researchers want to understand how these molecules affect recovery and identify patient types that respond best. It may help improve treatment for people in the ICU with serious infections.
This study looks at how your immune system and inflammation affect your recovery in the intensive care unit. Researchers want to understand why some patients do better than others.
This study looks at how gut bacteria affect severe infections in the ICU. It tests whether the microbiome can be a source of sepsis and a target for treatment. If you are critically ill or a long-term sepsis survivor, you might help find new ways to prevent infections.
This study looks at markers of inflammation, infection, and immunity in patients who are in the critical care area. It aims to find early signs of how severe the illness might become, how well treatments work, and if infections will develop.
This study looks at patients in the intensive care unit who have a new infection with Candida (a type of fungus) despite taking strong antibiotics. It aims to better understand and diagnose these serious infections.
This study wants to learn how your immune system reacts to a serious infection (like sepsis) in the ICU. By looking at your immune cells, doctors hope to better predict your recovery and find the best treatment for you.
Hear when a new Critical Illness trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.