Tulisokibart for X-ray confirmed axial spondyloarthritis
Treatments studied
Part of Bones, joints & muscles clinical trials.
This study tests a new medicine called Tulisokibart for people with a type of inflammatory arthritis that affects the spine and pelvic joints, specifically when X-rays show changes. The goal is to see if it can reduce symptoms like pain and stiffness.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a diagnosis of axial spondyloarthritis (a type of inflammatory arthritis that mainly affects the spine and pelvic joints) with back pain that started before age 45 and has lasted at least 3 months.
- You must have changes on X-rays of your spine or pelvis that are typical of ankylosing spondylitis, confirmed by a central reader.
- Your disease must be active (causing symptoms) both at the screening visit and when you start the study.
- You must have tried at least one NSAID (like ibuprofen or naproxen) and it didn't help enough or caused side effects. You may not have used any biologic medications, or you may have tried up to two different kinds but they didn't work or caused side effects.
- You cannot have other types of inflammatory arthritis (like rheumatoid arthritis or psoriatic arthritis). You also cannot have had cancer (other than fully treated skin cancer) in the last 5 years, and you cannot have an active infection.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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