B Cells in Kidney Transplant Rejection Study
Treatments studied
Part of Immune system & allergy, Kidney & urinary clinical trials.
This study looks at certain immune cells (B cells) in the blood and kidney to better understand antibody-mediated rejection in kidney transplant patients. It might help doctors find new ways to diagnose or treat this type of rejection.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are an adult who has received a kidney transplant.
- You are scheduled for a kidney biopsy or removal of the transplanted kidney.
- You agree to take part in the study and sign a consent form.
- You have health insurance coverage.
- You do not have a current kidney infection or BK virus infection.
- You are not pregnant or breastfeeding, and you are not under legal guardianship.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new treatment called BiTE (a type of immunotherapy that helps your immune cells attack harmful antibodies) for people whose transplanted kidney is being damaged by chronic active antibody-mediated rejection. The goal is to see if it can safely slow or stop this damage.
This study is for people with a kidney transplant who are in the hospital for a biopsy because their doctor suspects rejection. Researchers want to see if a simple blood or urine test can detect rejection, which might make future biopsies less necessary.
This study looks at how memory B cells (a type of immune cell) relate to antibodies against HLA in people waiting for a kidney transplant. It aims to better understand immune responses, which could help improve transplant matching and outcomes.
This study looks at molecular changes in kidney transplants that have microvascular inflammation (a type of injury). It aims to better understand why some transplants get this inflammation, which could lead to better treatments.
This study looks for pieces of kidney DNA in the blood of people who have a kidney transplant and need a biopsy. The goal is to see if this test can help doctors know if the kidney is being rejected without needing a biopsy.
This study looks at how the body’s immune system responds when a kidney transplant shows signs of rejection, using a planned kidney biopsy. It may help doctors better understand what drives rejection and how to improve care in the future.
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