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NCT07134998Possibly a fitRecruiting

Study of HRS-6093 for advanced solid tumors with KRAS G12D mutation

Advanced KRAS G12D Mutant Solid Tumors

Part of Cancer clinical trials.

This trial tests a new drug, HRS-6093, for people with advanced solid tumors that have a specific genetic change called KRAS G12D. The goal is to see if the drug is safe and effective for those who have not responded to or cannot tolerate other treatments.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
153 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You must be between 18 and 75 years old.
  • Your tumor must have a KRAS G12D mutation, confirmed by a previous test or a central lab.
  • You must have tried standard treatment, or be unable to tolerate it, or not have received it yet.
  • You need to be in fairly good physical condition (ECOG score 0 or 1).
  • You must have at least one measurable tumor and be willing to provide a tumor tissue sample.
  • Your organs must be working well enough, and you cannot have serious health issues like untreated brain metastases, active infections, or recent blood clots.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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