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NCT07143448Possibly a fitRecruiting

Study of HS235 for pulmonary arterial hypertension in adults

Pulmonary Arterial Hypertension

Part of Lungs & breathing clinical trials.

This trial tests an experimental drug called HS235 for people with pulmonary arterial hypertension (PAH), a condition of high blood pressure in the lungs. It aims to see if the drug can help improve symptoms and exercise ability.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
90 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years old or older.
  • Your body mass index is between 18.5 and 40, and you weigh 120 kg (about 265 lbs) or less.
  • You have a confirmed diagnosis of PAH (WHO Group 1) and are in functional class II to IV, meaning you have symptoms like shortness of breath but are not bedridden.
  • You are currently taking at least 2 approved PAH medications and diuretics (water pills) at stable doses.
  • You can walk between 150 meters (about 164 yards) and 500 meters (about 547 yards) in 6 minutes.
  • You do not have any other type of pulmonary hypertension (like from heart or lung disease), recent major surgery, or serious heart or lung conditions.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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