Using a special scan to find scar tissue in Crohn's disease
Part of Digestive system clinical trials.
This study uses a special imaging tracer (FAPI) to find scar tissue in the small intestine of people with Crohn's disease. The goal is to see if this scan can help doctors better understand which parts of the intestine are scarred, which may guide treatment decisions.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have Crohn's disease that affects the last part of your small intestine (the ileum) or the area where a surgery was done before.
- You are about to start a biologic medicine for your Crohn's disease.
- You are not pregnant, breastfeeding, or planning to become pregnant.
- You do not have very poor kidney function (eGFR under 30) or a known allergy to the contrast dye used in scans.
- You can lie still in a scanner for the PET/MRI or PET/CT and do not have claustrophobia or a metal implant that prevents MRI.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study is testing a new imaging method that uses a special PET/MR scan to see how active Crohn's disease is in your bowel. The scan uses a harmless radioactive tracer that attaches to scar tissue, which may help doctors better understand the disease and guide treatment.
This study uses a special PET-MRI scan to look at inflammation and blood flow in the small intestine of people with Crohn's disease. It may help doctors better understand disease activity in the gut.
This study checks whether adding an extra, cross-body “transmural” evaluation (looking at inflammation throughout the bowel) improves care for adults with Crohn’s who are starting or receiving biologic (biotherapy) treatment. It uses close follow-up with stool calprotectin (a marker of gut inflammation) to see if this approach helps control inflammation.
This study looks at how Crohn’s disease healing shows up on a special MRI (MRE) and tries to better define what “healed” means. It may help your care team track healing more accurately, especially inside the bowel.
This study tests a new PET scan with a tracer called 68Ga-FAPI-46 to see how well it can find and measure scarring (fibrosis) in the small bowel caused by Crohn's disease. It may help doctors better understand and manage bowel damage.
This trial uses a special PET scan called FAPi-PET to look for inflammation and scarring in the gut. It may help doctors better understand your condition and guide treatment.
Hear when a new Crohn Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.