CBD to prevent nerve damage from oxaliplatin in colorectal cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests if cannabidiol (CBD) can prevent nerve damage (neuropathy) caused by the chemotherapy drug oxaliplatin. If you have colorectal cancer that has spread or cannot be removed by surgery and you are about to start oxaliplatin, you may be able to join.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have colorectal cancer that has spread or cannot be removed by surgery, and you are scheduled to get oxaliplatin chemotherapy for at least 3 months.
- You have not had platinum chemotherapy before (like oxaliplatin or cisplatin).
- You do not currently have any nerve damage symptoms (like tingling or numbness).
- Your liver function is adequate, as shown by blood tests (bilirubin and liver enzymes within certain limits).
- You have not used recreational marijuana more than 4 times a month in the last 90 days, and you are willing to stop medical cannabis at least 1 week before starting.
- You do not have a history of seizures, certain mental health conditions, or are taking specific medications that interact with CBD.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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