Coenzyme Q10 to prevent nerve damage from chemotherapy
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests whether taking coenzyme Q10 (a natural substance) can help prevent nerve damage caused by the chemotherapy drug oxaliplatin in people with stage III colorectal cancer. If successful, it could reduce pain, numbness, or tingling during treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have stage III colorectal cancer that has been confirmed by a biopsy.
- You are scheduled to receive a specific chemotherapy regimen called modified FOLFOX-6.
- You must be 18 years or older.
- Your blood counts, kidney function, and liver function must be within normal limits (your doctor will check this).
- You must be in good physical condition (able to do normal activities without help).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at ways to prevent numbness or nerve pain in the hands and feet that can happen from oxaliplatin treatment. It includes people with colon or rectal cancer who will be getting standard chemotherapy with capecitabine plus oxaliplatin.
This study tests if foot reflexology can help prevent nerve damage caused by a chemotherapy drug called oxaliplatin in people with colorectal cancer. If it works, it could reduce pain, tingling, or numbness in the hands and feet.
This study tests whether acupuncture can reduce nerve pain caused by oxaliplatin chemotherapy in people with gastrointestinal cancers. It may help lessen symptoms like tingling, numbness, or burning that affect hands or feet.
This trial tests whether ketotifen can protect against nerve damage (called peripheral neuropathy) caused by oxaliplatin, a common chemotherapy used for stage III colon cancer. If it works, it may help reduce tingling, numbness, or burning pain in the hands and feet.
This trial tests whether two common medications, memantine and rosuvastatin, can protect nerves during colorectal cancer treatment. If you are about to start chemotherapy with FOLFOX or XELOX, this study may help reduce nerve damage.
This trial tests whether taking vitamin C and coenzyme Q10 can help protect your kidneys from damage caused by certain chemotherapy drugs (cisplatin and gemcitabine). It may be an option if you are about to start chemotherapy for cancer and have healthy kidneys.
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