Coenzyme Q10 to prevent nerve damage from chemotherapy
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests whether taking coenzyme Q10 (a natural substance) can help prevent nerve damage caused by the chemotherapy drug oxaliplatin in people with stage III colorectal cancer. If successful, it could reduce pain, numbness, or tingling during treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have stage III colorectal cancer that has been confirmed by a biopsy.
- You are scheduled to receive a specific chemotherapy regimen called modified FOLFOX-6.
- You must be 18 years or older.
- Your blood counts, kidney function, and liver function must be within normal limits (your doctor will check this).
- You must be in good physical condition (able to do normal activities without help).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at ways to prevent numbness or nerve pain in the hands and feet that can happen from oxaliplatin treatment. It includes people with colon or rectal cancer who will be getting standard chemotherapy with capecitabine plus oxaliplatin.
This study tests if foot reflexology can help prevent nerve damage caused by a chemotherapy drug called oxaliplatin in people with colorectal cancer. If it works, it could reduce pain, tingling, or numbness in the hands and feet.
This trial is testing two medications (memantine and rosuvastatin) that may protect your nerves from damage during chemotherapy. It is for people with stage III or IV colorectal cancer who are about to start a specific chemo regimen (FOLFOX or XELOX).
This trial tests whether ketotifen can protect against nerve damage (called peripheral neuropathy) caused by oxaliplatin, a common chemotherapy used for stage III colon cancer. If it works, it may help reduce tingling, numbness, or burning pain in the hands and feet.
This trial tests whether taking vitamin D supplements can prevent nerve damage (a common side effect) caused by paclitaxel chemotherapy in women with early-stage breast cancer. If you have low vitamin D levels, you may be able to join.
This trial tests whether taking vitamin C and coenzyme Q10 can help protect your kidneys while you receive chemotherapy with cisplatin and gemcitabine. It may reduce the risk of kidney damage from these treatments.
Hear when a new Colorectal cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.