A weight-loss medication for PCOS in teenage girls
Treatments studied
Part of Hormones & metabolism clinical trials.
This trial tests a medication called a GLP-1 agonist (a type of drug that helps with weight loss and blood sugar) to see if it can improve how your brain and reproductive system work, which may help with PCOS symptoms and fertility. The study is for teenage girls with PCOS who are also obese, and it could offer an option if lifestyle changes alone haven't been enough.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a female between 12 and 18 years old, and you have had your period for at least 2 years.
- You have been diagnosed with PCOS, which means you have irregular periods (less than 21 days or more than 35 days apart) and higher-than-normal levels of male hormones (testosterone).
- Your weight is in the obese range, meaning your BMI is at or above the 95th percentile for your age and gender.
- You have tried lifestyle changes (like diet or exercise) for at least 4 months, but your PCOS symptoms and weight have not improved enough.
- You are not currently pregnant, and you have not been pregnant in the past.
- You do not have diabetes, thyroid problems, or certain other medical conditions like a history of pancreatitis or a specific type of thyroid cancer.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new medication that combines two hormone-like drugs to treat polycystic ovary syndrome (PCOS), a condition affecting ovulation and hormone balance. The trial aims to see if this dual-action drug can improve irregular periods and other PCOS symptoms better than current treatments.
This trial tests whether a class of drugs called GLP-1 receptor agonists (often used for diabetes and weight loss) can improve pregnancy outcomes in women with polycystic ovary syndrome (PCOS) who are overweight or obese. If you have PCOS and a BMI between 28 and 35, you may be eligible to participate.
This study tests whether a class of diabetes drugs called GLP-1 receptor agonists can improve fertility in overweight women with polycystic ovary syndrome who want to conceive. These drugs help with weight and blood sugar, which may improve ovulation and pregnancy chances.
This study tests whether the weight-loss drug orlistat can improve blood sugar, hormones, and other metabolic measures in women with polycystic ovary syndrome (PCOS). If you have PCOS and are overweight, this treatment might help with symptoms like irregular periods and excess hair growth.
This trial tests if liraglutide, a weight-loss medication, can help obese women with PCOS who have a frozen embryo achieve pregnancy. It aims to improve fertility outcomes by aiding weight loss before embryo transfer.
This study tests if tirzepatide (a once-weekly injection) can improve periods and metabolic health in women with PCOS who are overweight. If you have PCOS, irregular cycles, and a BMI of 27 or higher, you might qualify.
Hear when a new Obesity (Disorder) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.