Clin2
NCT07177339Possibly a fitRecruiting

Testing depemokimab for COPD with type 2 inflammation

Pulmonary Disease, Chronic Obstructive

Treatments studied

Part of Lungs & breathing clinical trials.

This study tests an early treatment called depemokimab for people with moderate to severe COPD who have a type of inflammation linked to high eosinophils. It aims to reduce flare-ups and improve breathing.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
1,196 people
Ages
40 years to 75 years
Study type
Interventional

Who can take part

  • You have moderate to severe COPD and your blood test shows high eosinophils (a type of white blood cell linked to inflammation)
  • You have had at least 1 moderate flare-up in the past year and have other risk factors for future flare-ups
  • You are a current or former smoker with at least a 10 pack-year smoking history
  • You take combination inhaler therapy (like ICS+LABA or LABA+LAMA or triple therapy) for at least 3 months
  • You have a BMI of 16 or higher and no other major lung disease like asthma

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06959095Recruiting· Phase 3
Depemokimab for adults with COPD and type 2 inflammation

This trial tests a new biologic medicine called depemokimab, given as an injection, to see if it reduces flare-ups (exacerbations) in people with COPD who have a specific type of inflammation (high eosinophils). It may help if you have frequent flare-ups despite using your regular inhalers.

Bakersfield, California
NCT06961214Recruiting· Phase 3
Depemokimab for COPD with type 2 inflammation

This study tests a new biologic medicine, given as an injection, to see if it can reduce flare-ups in adults with COPD who have a certain type of inflammation. It may help people who still have frequent exacerbations despite using their current inhalers.

Sheffield, Alabama
NCT07780669Recruiting· Phase 3
Study of a new drug for moderate to severe COPD in smokers

This study tests a new medication (GSK5784283) for people with moderate to severe COPD who have a certain type of inflammation (eosinophilic). Participants must be on standard inhaler therapy and have a history of smoking. The trial will compare the new drug to a placebo.

Doral, Florida
NCT06979323Recruiting· Phase 3
Depemokimab study for asthma with imaging and bronchoscopy

This study tests depemokimab, an injectable biologic, to see how it works in the lungs of people with severe asthma. You would get the drug and have special imaging and a bronchoscopy (a tube with a camera placed into your airways to take tiny tissue samples) so doctors can understand how the medicine reduces inflammation.

Brooksville, Florida
NCT07671001Recruiting· Phase 3
Study of depemokimab for children (6-11) with asthma

This trial tests if a new medicine, depemokimab, can help children aged 6 to 11 whose asthma is not well controlled with their current inhalers and who have a type of inflammation called eosinophilic asthma. It may reduce asthma attacks and improve symptoms.

Mobile, Alabama
NCT07456033Recruiting· Phase 3
Depemokimab for adults and teens with type 2 asthma

This study tests a new medicine called depemokimab, given as an injection, to see if it can reduce asthma attacks in people with a specific type of asthma (type 2 high). If you have had asthma for several years and have had recent attacks despite using regular inhalers, this trial might be an option for you.

Little Rock, Arkansas

Hear when a new Pulmonary Disease, Chronic Obstructive trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.