Nerve block for chronic back pain from disc herniation
Part of Bones, joints & muscles clinical trials.
This study tests whether a nerve block (called an erector spinae plane block) can help relieve chronic low back and leg pain caused by a herniated disc at L4-L5 or L5-S1, when other treatments have not worked.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have chronic low back pain that has lasted more than 6 weeks.
- You have pain that goes into your leg (radicular pain) caused by a disc problem at L4-L5 or L5-S1, seen on an MRI.
- You have not had any back surgery before.
- You have tried other treatments like painkillers or physical therapy and they didn't work well enough.
- You do not have conditions like uncontrolled diabetes, spine deformity, spinal stenosis, infection, bleeding problems, or rheumatic disease.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two types of pain-relieving nerve blocks (TLIP and QIP) given during back surgery to see which one provides better pain control after the operation. If you're having lumbar disc surgery, this could help you recover with less pain.
This trial tests whether a nerve block (called an erector spinae plane block) given before surgery can reduce the amount of pain medicine and anesthesia needed during lumbar disc surgery. It may help people have less pain and fewer side effects.
This study compares two ways to manage pain during and after surgery for a single-level lumbar disc herniation: an erector spinae plane block (a numbing injection near the spine) versus intrathecal morphine (a painkiller given into the spinal fluid). The goal is to see which approach reduces the amount of anesthesia needed during surgery, which may lead to a smoother recovery.
This study tests whether a nerve-blocking injection in the back muscles can relieve persistent back pain in people with ankylosing spondylitis (a condition causing spine inflammation and stiffness). The injection targets specific nerves to reduce pain while your current disease treatment continues.
This trial tests whether a targeted back/neck numbing injection (an erector spinae block) can help reduce the amount of opioid pain medicine needed after posterior cervical spine surgery. It also aims to support an “enhanced recovery” pathway so patients may recover more comfortably and potentially faster.
This trial tests whether an “ESP block” (a numbing injection near the spine) can help control pain during minimally invasive low back fusion surgery. If you’re having this surgery, the goal is to improve comfort and reduce pain medicine needs.
Hear when a new Lumbar Disc Herniation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.