Immunotherapy and chemotherapy with a probiotic supplement for advanced cancer
Part of Cancer, Immune system & allergy clinical trials.
This trial tests whether adding a probiotic (Lactobacillus Johnsonii) to standard chemotherapy and immunotherapy can help people with certain advanced solid tumors that have stopped responding to prior immunotherapy. It may help your immune system work better against the cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have one of these cancer types that has spread and can't be removed by surgery: a type of lung cancer, triple-negative breast cancer, or stomach/esophageal cancer with specific markers.
- You have already been treated with immunotherapy (PD-1 or PD-L1 inhibitors) and your cancer got worse during or within 12 weeks of that treatment.
- You have at least one tumor that can be measured on a scan.
- You are in good enough health to walk and take care of yourself (ECOG 0 or 1).
- You have not had certain immune-related side effects from prior immunotherapy that made you stop treatment, or any serious side effects.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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