New drug combo vs. standard for bedwetting in children
Treatments studied
Part of Kidney & urinary, Mental health, Women’s health & pregnancy clinical trials.
This trial tests a new medication (Omegapres) against the usual combination of two drugs (Solifenacin and Mirabegron) to see which works better for children with nighttime bedwetting (primary mono-symptomatic nocturnal enuresis). If your child has only bedwetting at night and no other bladder or bowel issues during the day, this study might help find a more effective treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your child wets the bed at night only, not during the day.
- Your child does not have any bowel problems, such as constipation or soiling.
- Your child does not have a diagnosed mental health condition.
- Your child does not have any sleep-related breathing problems, like sleep apnea.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new treatment for children who wet the bed at night, called nocturnal enuresis. The goal is to see if it helps children ages 6 to 18 who have had this problem since infancy.
This study tests whether adding pelvic floor muscle training (exercises for the muscles that help control urination) to a medicine called desmopressin works better than medicine alone for children who wet the bed at night. It may be an option if your child has not tried other treatments recently.
This study tests whether transcutaneous electrical nerve stimulation (TENS)—a gentle electrical therapy applied to the skin—can help children who continue to wet the bed at night despite other treatments. TENS may help retrain the bladder and improve nighttime control.
This study tests whether limiting screen time before bed plus taking a nightly medicine called desmopressin can help children who wet the bed at night. It may offer a new combined approach to reduce wet nights.
This trial tests whether injections of botulinum toxin (a medicine that relaxes muscles) into the bladder can help children who wet the bed at night or have trouble controlling their urine, even after trying other treatments. The goal is to see if this approach works better than current standard care.
This study tests two medicines (solifenacin and mirabegron) alone and together to see which works best for children with daytime wetting. It is for children ages 5 to 14 who still have accidents after trying non-drug treatments.
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