Clin2
NCT07214298Possibly a fitRecruiting

Combination treatment for advanced pancreatic cancer

Metastatic Pancreatic Ductal AdenocarcinomaStage IV Pancreatic Cancer AJCC v8

Treatments studied

Part of Cancer, Digestive system, Hormones & metabolism clinical trials.

This trial tests a new drug, pegcetacoplan, combined with a standard chemotherapy regimen called modified FOLFIRINOX, for people with pancreatic cancer that has spread to other parts of the body. The goal is to see if the combination helps control the cancer better than chemotherapy alone.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
35 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have pancreatic cancer that has spread beyond the pancreas (metastatic).
  • You are 18 years or older.
  • You are able to perform daily activities with minimal help (ECOG score of 0 or 1).
  • Your blood counts and liver/kidney function are within required limits.
  • You have not had chemotherapy for this cancer before, though you may have had gemcitabine-based treatment at least 6 months ago.
  • You are willing to receive vaccinations against certain bacteria (meningitis and pneumonia).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07490301Recruiting· Phase 2/Phase 3
Study of a new drug combo for first-line metastatic pancreatic cancer

This trial tests a new targeted drug, telisotuzumab adizutecan, combined with standard chemotherapy (FOLFOX) for people with advanced pancreatic cancer that has spread. The goal is to see if this combination works better than current treatments.

New Haven, Connecticut
NCT07226856Recruiting· Phase 2
New combo for advanced pancreatic cancer

This trial tests a new drug (BMS-986340) plus standard chemo for people whose pancreatic cancer has spread or come back. The goal is to see if this combination works better.

Scottsdale, Arizona
NCT04005690Recruiting· Early Phase 1
Targeted drug treatment for pancreatic cancer using pathway changes

This early-phase trial tests how well targeted medicines (and possibly an immunotherapy drug) work for people with pancreatic cancer that can’t be fully removed with surgery or has spread. It also looks at whether the treatment is safe and can shrink or control tumors by blocking specific cancer pathways.

Portland, Oregon
NCT07165951Recruiting· Phase 3
Study of new drug combo for first treatment of advanced pancreatic cancer

This trial tests a new combination of drugs (TQB2868 injection plus anlotinib capsules) compared to standard chemotherapy for people with pancreatic cancer that has spread to other parts of the body and has not been treated before.

Hefei, Anhui
NCT07348107Not yet recruiting· Phase 1
Combination treatment for advanced pancreatic cancer

This trial tests a new combination of drugs (ATRA, SDK002, chemotherapy, and an immunotherapy) for people with advanced pancreatic cancer that cannot be removed by surgery. The goal is to see if this combination can help shrink or control the cancer.

London, Ontario
NCT07829185Not yet recruiting· Phase 1
Chemotherapy plus pentamidine for advanced pancreatic cancer

This study tests a combination of two drugs—a standard chemotherapy called FOLFIRINOX and an investigational drug called pentamidine—in people with advanced pancreatic cancer. The goal is to see if this combination is safe and effective, and it may slow tumor growth.

Oklahoma City, Oklahoma

Hear when a new Metastatic Pancreatic Ductal Adenocarcinoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.