Clin2
NCT07216781Possibly a fitActive, not recruiting

Klotho gene therapy safety trial

Healthy Adults

This trial tests a new gene therapy that uses a harmless piece of DNA (called a plasmid) to help your body make more Klotho, a protein linked to healthy aging. The goal is to see if it's safe and whether it might slow aging or improve health.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
14 people
Ages
23 years to 90 years
Study type
Interventional

Who can take part

  • You must be open to changes in your appearance or body shape.
  • Women who could become pregnant must agree to use birth control and take pregnancy tests.
  • You cannot have a history of cancer, or any medical condition that could be made worse by the treatment.
  • You must not have had any gene therapy in the past year.
  • You must be able to give written permission (informed consent) to join the study.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07544420Not yet recruiting· Phase 1
Testing a New mRNA Therapy in Healthy Adults

This is an early-stage trial testing a new type of treatment called mRNA therapy that helps your body make missing proteins. Researchers are enrolling healthy volunteers to understand how safe and well-tolerated this approach is.

Roatán, Bay Islands
NCT07443826Recruiting· Phase 1/Phase 2
Gene therapy for age-related muscle loss and heart health

This trial tests a gene therapy that may help rebuild muscle and improve blood vessel growth in people ages 35 to 75. It's designed for those with stable health conditions and no history of cancer, heart disease, blood clots, or diabetes.

Coxen Hole, Bay Islands
NCT06877377Not yet recruiting
Stem cell gene therapy study for aging adults

This trial tests a new way to rebuild your blood stem cells to possibly slow down aging. It is for healthy adults aged 45 to 65 without serious illnesses or recent cancer.

NCT07215403Not yet recruiting· Phase 2
Gene therapy study for advanced Parkinson's disease

This trial tests a gene therapy for people with advanced Parkinson's disease (at least 10 years since diagnosis). It uses a special infusion to deliver treatment directly into the brain. The goal is to see if it can improve motor symptoms.

Cleveland, Ohio
NCT06458010Recruiting· Early Phase 1
Gene therapy trial for inherited high cholesterol

This trial tests a new gene therapy called YOLT-101 for people with familial hypercholesterolemia, a genetic condition that causes very high cholesterol. The treatment aims to lower cholesterol levels and reduce heart risks.

Shanghai, Shanghai Municipality
NCT07085195Not yet recruiting· Early Phase 1
Gene therapy for Parkinson's disease safety study

This study tests a new gene therapy (chemogenetics) to see if it is safe and how well it works for people with Parkinson's disease. The treatment involves a one-time infusion of a modified virus into the brain to help control movement symptoms.

Shanghai

Hear when a new Healthy Adults trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.