Gene therapy study for advanced Parkinson's disease
Part of Brain & nervous system clinical trials.
This trial tests a gene therapy for people with advanced Parkinson's disease (at least 10 years since diagnosis). It uses a special infusion to deliver treatment directly into the brain. The goal is to see if it can improve motor symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 45 and 75 years old.
- You have had Parkinson's disease for more than 10 years.
- You have moderate to advanced Parkinson's (Hoehn and Yahr stage 3 or 4 when off medication).
- Your movement symptoms (MDS-UPDRS Part III score) are above 40 when off medication.
- You have at least a 30% improvement in movement symptoms after taking levodopa.
- You have not had brain surgery (like deep brain stimulation) or prior gene/cell therapy.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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