Comparing two seizure prevention medicines for preeclampsia
Treatments studied
Part of Brain & nervous system, Women’s health & pregnancy clinical trials.
This study compares two medicines, levetiracetam and magnesium sulfate, to see which is better at preventing seizures in pregnant or postpartum women with severe preeclampsia. If you are at risk for seizures, this trial may help find a safer or more effective prevention option.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 19 years or older and pregnant or recently gave birth.
- You have been diagnosed with severe preeclampsia, superimposed preeclampsia, or HELLP syndrome.
- You are at risk for seizures and need preventive treatment.
- You have not had magnesium sulfate in the last 2 hours or it has been more than 48 hours since your last dose.
- You are admitted to the hospital or planning to deliver soon.
- You are at least 32 weeks pregnant.
- You do not have a history of epilepsy or seizures unrelated to pregnancy.
- You are not allergic to levetiracetam or magnesium sulfate.
- You do not have severe kidney problems (low urine output).
- You are not planning comfort care only for your baby.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how well the intravenous (IV) medicine labetalol lowers blood pressure in women with severe preeclampsia, a serious pregnancy complication. It aims to identify which patients might need different or additional treatment to control their blood pressure.
This study looks at different ways to give magnesium sulphate to women with severe preeclampsia to find the best treatment plan.
This study looks at whether certain blood tests can help doctors manage high blood pressure after delivery in people with severe preeclampsia. It compares the usual care with additional blood tests to see if they improve recovery and reduce complications.
This trial studies how certain blood markers and brain-wave signals change in pregnant people with severe preeclampsia, especially when it leads to eclampsia (seizures). The goal is to better understand warning signs and treatment response to keep mother and baby safer.
This study looks at two medicines (phenytoin and levetiracetam) to see which works better for treating or preventing seizures that can happen after a traumatic brain injury. It aims to find the safest and most effective option for patients.
This study tests whether giving magnesium sulphate (a mineral treatment) to pregnant women at risk of delivering very early (32–35 weeks) can protect the baby's brain and nervous system. The treatment is given before labor starts.
Hear when a new Severe Preeclampsia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.