Clin2
NCT07224932Possibly a fitNot yet recruiting

CBD for Restless Legs Syndrome

Restless Leg Syndrome

Treatments studied

Part of Brain & nervous system, Mental health clinical trials.

This trial tests if a CBD extract can help reduce moderate-to-severe restless legs syndrome symptoms. You'll take the study medication for several weeks and be monitored for side effects and improvements.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
60 people
Ages
18 years to 79 years
Study type
Interventional

Who can take part

  • You are between 18 and 79 years old.
  • You have been diagnosed with restless legs syndrome (RLS) and your symptoms are moderate or severe.
  • You have not changed your RLS medications for at least 4 weeks before starting the study.
  • You have a friend or family member who knows you well and can help with assessments during the study.
  • You agree to not use cannabis or certain other drugs during the study, and you can limit acetaminophen to 1 gram per day.
  • You have reliable transportation to and from study visits.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07642089Recruiting
Stretching and strength training for restless legs in pregnancy

This study tests whether gentle stretching and strength exercises can help pregnant women with restless leg syndrome—a condition that causes uncomfortable sensations in the legs and disrupts sleep. The goal is to see if these exercises reduce symptoms and improve sleep quality during pregnancy.

Lahore, Punjab Province
NCT06863740Recruiting
Cannabis for Restless Legs Syndrome

This study tests whether cannabis can help people with Restless Legs Syndrome that has not improved with standard treatments. If you have RLS and other treatments haven't worked well, you may be able to join.

Toronto, Ontario
NCT07453862Recruiting· Phase 1
New drug for restless legs syndrome: efficacy and safety study

This trial tests a new drug (a calcium channel modulator) to see how well it works and how safe it is for people with moderate to severe restless legs syndrome (RLS). It may offer a new treatment option for those with typical or variant RLS.

Beijing, Beijing Municipality
NCT07571733Not yet recruiting
Spinal cord stimulation for severe restless leg syndrome

This study tests whether a small implanted device that sends electrical signals to the spinal cord can help people with severe restless leg syndrome (RLS) who haven't improved with medications. RLS causes uncomfortable sensations in the legs, especially at night, and this treatment may provide relief when standard drugs don't work.

Gravesano, Canton Ticino
NCT07780032Not yet recruiting
Spinal cord stimulation for severe restless legs syndrome

This study tests whether a device that sends mild electrical pulses to the spinal cord can reduce the symptoms of restless legs syndrome (RLS) in people who have not gotten enough relief from medications. If successful, it could offer a new treatment option for severe RLS.

Birmingham, Alabama
NCT07397247Not yet recruiting
Device therapy for restless legs with medication worsening

This study tests a device that sends mild electrical pulses to nerves in your lower legs to calm RLS symptoms, especially at night. It is for people whose RLS has worsened despite taking dopamine-agonist medications.

Innsbruck, Tyrol

Hear when a new Restless Leg Syndrome trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.