Study of Combogesic 325 for teens with pain after bone surgery
Treatments studied
Part of Pain clinical trials.
This trial tests a combination painkiller (Combogesic 325) for teenagers aged 12 to 17 who have moderate to severe pain after orthopedic (bone) surgery. It aims to see if this drug provides better pain relief than standard treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 12 to 17 years old.
- You are having planned bone (orthopedic) surgery that requires staying in the hospital for at least 24 hours.
- You have moderate to severe pain within 6 hours after your surgery (pain score of 50 or higher on a 0-100 scale).
- You have not taken any NSAID (like ibuprofen) or acetaminophen (Tylenol) within 5 half-lives (about 2-3 days for most) before the study drug.
- You are not allergic to opioids, NSAIDs, or acetaminophen.
- If female and able to have children, you must use reliable birth control and have a negative pregnancy test. If male and sexually active, you must also use reliable birth control.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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