Treatment
Acetaminophen clinical trials
We’re tracking 63 recruiting studies that include Acetaminophen, each written for real people, not researchers, below.
Recruiting studies
- NCT07759349RecruitingEarly Phase 1
Pain relief choices after root canal treatment
This study compares three different pain relievers to see which works best for pain after a single-visit root canal. It may help find better ways to manage post-procedure discomfort.
Karachi, SindhAges 18–60 - NCT05425355RecruitingPhase 4
IV versus oral acetaminophen after hip-fracture surgery
This trial compares giving acetaminophen (Tylenol) through a vein versus by mouth after hip-fracture surgery. It may help find which method works better for pain control and recovery in adults.
Toronto, OntarioAges 60 years+ - NCT03825809RecruitingPhase 2/Phase 3
Non-narcotic pain medicine after labral shoulder surgery
This trial studies whether a non-narcotic pain plan after labral (shoulder) surgery can control pain as well as or better than usual treatment. It may help patients avoid opioid (narcotic) pain medicines after surgery.
Detroit, MichiganAges 18 years+ - NCT05878015Enrolling by invitationPhase 4
IV acetaminophen for small bowel blockage symptoms
This Phase 4 study tests whether giving acetaminophen through a vein helps people with a small bowel obstruction (a blockage in the intestines) that is causing abdominal pain. It’s looking for a benefit in pain control and how people do during treatment.
Jacksonville, FloridaAges 18 years+ - NCT07525219RecruitingPhase 3
Pain Relief During Stereotactic Head Frame Placement
This study compares a new pain medication called suzetrigine with acetaminophen (Tylenol) for patients who need a stereotactic head frame placed as part of their scheduled medical procedure. The frame holds your head still during brain imaging or treatment.
Winston-Salem, North CarolinaAges 21 years+ - NCT07400471RecruitingEarly Phase 1
Pain relief before root canal: a medicine combination
This trial tests whether a combination of pain medicines given before a root canal can lower pain afterward. It is for people who have moderate to severe tooth pain and are healthy enough for standard treatment.
Chittagong, ChattogramAges 18 years+ - NCT07620665Recruiting
Pain Relief Medicine for Gallbladder Removal Surgery
This trial tests a new pain medication called opiranserin for patients having minimally invasive gallbladder surgery (a small-cut procedure). The goal is to see if it safely reduces pain after surgery.
SeoulAges 19 years+ - NCT07709598RecruitingPhase 2/Phase 3
HL-1186 for pain after abdominal surgery
This study tests a new painkiller called HL-1186 for people having abdominal surgery. If you qualify and enroll, you will receive the drug after surgery to see if it safely helps reduce your pain better than a placebo (a pill with no medicine).
Chengdu, SichuanAges 18–75 - NCT03823534RecruitingPhase 3
Study pain control after preventive femur bone surgery
This Phase 3 study tests a pain medicine plan used after preventive surgery to place a metal rod inside the thigh bone (femur) before a fracture happens. The goal is to find an approach that controls post-surgery pain while being safe for the right patients.
St Louis, MissouriAges 18 years+ - NCT07699601RecruitingPhase 2/Phase 3
Testing a pain tablet after orthopedic surgery
This trial tests an investigational tablet called HL-1186 for controlling pain after orthopedic surgery. It explores whether the drug can safely reduce moderate to severe pain when given after the procedure.
Changsha, HunanAges 18–75 - NCT05340582RecruitingPhase 2
Ibuprofen plus acetaminophen for a heart condition in very premature babies
This Phase 2 study tests whether giving ibuprofen together with acetaminophen improves outcomes for an important heart connection (PDA) in extremely premature infants. It compares how this medicine approach affects the baby’s heart-related measurements and short-term progress.
Newcastle, New South WalesAges Up to 6 months - NCT05722782RecruitingPhase 2
Kidney stone pain treatment after ER discharge
This study compares an anti-inflammatory pain medicine (NSAID) given by mouth versus acetaminophen (paracetamol) or placebo after you leave the emergency room for a “renal colic” (kidney stone pain). It looks at whether the NSAID helps control pain better and whether it’s safe for people with uncomplicated kidney stone pain.
MonastirAges 18 years+ - NCT06479122RecruitingPhase 4
Pain relief after C-section: acetaminophen with or without ibuprofen
This study compares two common pain relievers after C-section: acetaminophen alone versus acetaminophen plus ibuprofen. It aims to see if the combination offers better pain control after childbirth.
SeoulAges 19 years+ - NCT06613178RecruitingPhase 4
IV acetaminophen for heart surgery recovery
This trial tests if giving acetaminophen (Tylenol) through a vein after heart surgery can help patients recover better. You may be a good fit if you are having planned heart surgery that is not an emergency.
Vancouver, British ColumbiaAges 18 years+ - NCT07102641RecruitingPhase 4
Comparing pain relief methods after c-section
This study compares two ways of giving pain medication after a cesarean section to see which works better. It may help find the best approach to manage pain after surgery while reducing the need for stronger medications.
Philadelphia, PennsylvaniaAges 16 years+ - NCT07368738Enrolling by invitationPhase 4
IV Pain Meds for Shock Wave Lithotripsy
This study tests whether giving two pain relievers—acetaminophen (Tylenol) and ketorolac (an anti-inflammatory)—through an IV during shock wave lithotripsy helps control pain better than standard care. You may qualify if you need this kidney stone procedure and don't have certain health conditions.
Saint John, New BrunswickAges 19 years+ - NCT07710729RecruitingPhase 1
How UBT251 Affects Birth Control and Stomach Emptying
This study tests a new medicine, UBT251, to see if it affects how birth control pills work and how quickly food leaves the stomach. It is for women with overweight or obesity who cannot get pregnant.
Montreal, QuebecAges 18–65 - NCT06824467RecruitingPhase 3
Maintenance Therapy Study for Recurrent Ovarian Cancer
This study tests a new maintenance treatment (sacituzumab tirumotecan) versus standard care for people with ovarian cancer that has come back after responding to platinum-based chemotherapy. The goal is to see if it can keep the cancer from growing longer and improve quality of life.
Birmingham, AlabamaAges 18 years+ - NCT07570173RecruitingPhase 2/Phase 3
MK-1045 for Hard-to-Treat B-Cell Leukemia
This trial tests a new drug called MK-1045 in patients whose acute lymphoblastic leukemia (a blood cancer) has come back or stopped responding to previous treatments. The goal is to see if this drug can help control the cancer when other options haven't worked.
Copenhagen, Capital RegionAges 12 years+ - NCT07738614RecruitingPhase 1
Testing an investigational weight loss medicine for adults with overweight or obesity
This study tests an experimental medicine (eloralintide) to see if it can help people with overweight or obesity lose weight without having diabetes. The medicine works by affecting hormones that help control appetite and body weight.
San Antonio, TexasAges 18–65 - NCT07765823Recruiting
N-acetylcysteine for liver failure not caused by acetaminophen
This trial tests whether the drug N-acetylcysteine (NAC) can help people with sudden liver failure that is not caused by acetaminophen (like Tylenol). If you qualify, you may receive NAC, which might help your liver recover.
Lahore, Punjab ProvinceAges 18–60 - NCT07661459RecruitingPhase 2
Antihistamine and aspirin with immunotherapy for solid tumors
This trial tests whether taking a daily antihistamine (like Claritin) and a daily aspirin alongside your immunotherapy can make the treatment work better. It's for people with solid tumors who are about to start a PD-1 or PD-L1 blocker.
Lexington, KentuckyAges 18–99 - NCT07750639Enrolling by invitationPhase 4
Reducing painkiller use after hand surgery
This study tests a new approach to prescribing fewer opioid pain pills after hand, wrist, or elbow surgery. It aims to help reduce the risk of opioid misuse while still controlling pain after surgery.
Orlando, FloridaAges 18 years+ - NCT06878014RecruitingPhase 4
Morphine for pain relief after hip replacement surgery
This trial tests different doses of morphine given during spinal anesthesia to find the safest and most effective way to control pain after hip replacement surgery. If you are having a total hip replacement, you may be able to join.
Sosnowiec, Silesian VoivodeshipAges 18–75
What Acetaminophen is being studied for
Conditions with recruiting Acetaminophen studies.
Common questions
- Are there clinical trials studying Acetaminophen?
- Yes. Clin2 currently lists 63 recruiting studies that include Acetaminophen, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Acetaminophen trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Acetaminophen an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Acetaminophen or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.