Clinical trials
Post Operative Pain, Acute clinical trials
Below are recruiting post operative pain, acute clinical trials, each written for real people, not researchers. We’re tracking 41 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07745972Recruiting
Pain relief block for gallbladder surgery
This trial tests a numbing injection near the ribs to reduce pain after laparoscopic gallbladder removal. It may help you recover with less discomfort.
IstanbulAges 18–80 - NCT06843174RecruitingPhase 4
Methadone for pain during and after spine surgery
This trial tests if giving a single dose of methadone right before and during spine surgery can help manage pain better. If it works, you might need fewer other pain medicines after surgery.
Toronto, OntarioAges 18–65 - NCT05854914Recruiting
Smartphone hypnosis to reduce pain after emergency appendix surgery
This study tests whether guided hypnosis on a smartphone can lower pain after emergency surgery for a complicated appendicitis. If you qualify, you’ll use the app during your recovery and also answer quick questions about your pain and anxiety.
NiceAges 18 years+ - NCT07738770Recruiting
Comparing two numbing techniques for pain relief after mastectomy
This trial tests two different numbing injections to see which one works better for pain after breast cancer surgery. If you are having a mastectomy, you may be able to join and help find a better way to manage pain.
Jakarta, DKI JakartaAges 18–60 - NCT05141591Recruiting
Anxiety before ENT surgery and opioid use after surgery
This trial looks at whether people’s anxiety before ear, nose, and throat (ENT) surgery affects how much pain medicine (opioids) they need after surgery. It may help doctors better plan pain control based on anxiety level and possibly gender-related patterns.
Vienna, State of ViennaAges 18 years+ - NCT05150795RecruitingEarly Phase 1
Testing pregabalin before surgery versus fentanyl during surgery
This trial compares two medicines used around the time of surgery—pregabalin given by mouth before surgery versus fentanyl given during surgery—to see which better controls pain after the operation. You might join if you’re a generally healthy surgical patient and aren’t using certain related medicines.
CairoAges 21–45 - NCT05534945Recruiting
Finds the best epidural pain dose after laparotomy surgery
This study tests different doses of epidural pain medicine to see what works best for pain control after laparotomy surgery. You might benefit from carefully tailored pain relief, but you must meet safety and communication requirements.
Montreal, QuebecAges 18–85 - NCT05754190Recruiting
Smartphone study of mood and symptoms in people with pain
This study uses a smartphone app to track daily pain and mood changes over about 4 months. It’s meant to learn patterns that could help better understand how mood and pain affect each other.
Providence, Rhode IslandAges 18 years+ - NCT05920200Recruiting
Study of hernia repair results by hernia location
This study looks at how different hernia repairs turn out depending on where the hernia is in the body. It uses existing medical records to understand which factors may influence recovery or outcomes after surgery.
Kaliningrad, Kaliningrad OblastAges 18–90 - NCT05920382Recruiting
Radiofrequency treatment for long-term knee pain after knee surgery
This trial studies whether a radiofrequency procedure can reduce chronic knee pain after knee replacement surgery. It may help people who still have bothersome pain between 6 months and 5 years after their operation, as long as their pain pattern and medications are stable.
Barcelona, CataloniaAges 18 years+ - NCT06123715RecruitingPhase 2
Vitamin C to reduce pain after knee replacement
This study tests whether taking vitamin C before and after knee replacement surgery can reduce long-term pain. You may be eligible if you are having knee replacement for osteoarthritis and are generally healthy.
Toronto, OntarioAges 18 years+ - NCT06158620RecruitingPhase 1/Phase 2
Nasal spray for pain after ureter stent placement
This trial tests whether a nasal spray form of the painkiller ketorolac can safely reduce pain from a ureteral stent after stone surgery. If you are having a ureteroscopy with stent placement, this might help you manage discomfort without stronger medications.
Dallas, TexasAges 18 years+ - NCT06466941Recruiting
Understanding acute pain after surgery
This study surveys surgical patients about their pain and emotional experience to better understand acute pain. You may help by answering questions or sharing your story.
Boston, MassachusettsAges 18 years+ - NCT06515691Recruiting
Nerve block for pain after weight loss surgery
This study tests a nerve block (an injection near the nerves) to see if it helps reduce pain after laparoscopic sleeve gastrectomy. The block is called a modified thoracoabdominal nerve plane block, and it may lead to better pain control and recovery.
Istanbul, BagcilarAges 18–65 - NCT06555107Recruiting
Pain before emergency surgery and long-term pain after
This study looks at whether pain you feel before emergency surgery affects long-term pain after the surgery. It may help doctors find ways to prevent chronic pain in patients who have emergency orthopedic (bone/joint) or abdominal (belly) surgery.
AmiensAges 18 years+ - NCT06661642Recruiting
Predicting pain after planned surgery
This study looks at whether we can predict how much pain you will feel after surgery. It aims to help doctors better manage pain after your operation.
AalborgAges 18 years+ - NCT06741696Recruiting
Saline rinsing after wisdom tooth removal
This trial tests whether using saline (salt water) at different temperatures after wisdom tooth surgery helps with healing and pain. It could help you recover more comfortably.
Rawalpindi, Punjab ProvinceAges Up to 59 years - NCT06779604Recruiting
Numbing medicine mix for arm surgery pain relief
This trial tests if adding two medicines, dexmedetomidine and dexamethasone, to the numbing shot around the arm's nerves can improve pain relief during and after upper arm or hand surgery.
Istanbul, UmraniyeAges 18–70 - NCT06864884RecruitingEarly Phase 1
Study of ARC-001 for wisdom teeth removal
This trial tests a new medicine called ARC-001 in people who are scheduled to have their wisdom teeth taken out. The goal is to see if it's safe and how it affects pain and healing.
Salt Lake City, UtahAges 18–55 - NCT06982625Recruiting
Numbing injection after hip replacement for pain relief
This trial tests whether an injection of numbing medicine near the hip can help control pain after a hip replacement surgery. It may be an option for people who have significant pain after their operation.
ParisAges 18 years+ - NCT07250399Recruiting
Pain after root canal treatment with different tools
This trial compares two different ways of cleaning a tooth's root canal to see which causes less pain during and after treatment. It is for people with severe tooth pain in an upper premolar.
CairoAges 20–50 - NCT07680998Recruiting
Pain monitor device for recovery after day surgery
This trial tests a device that monitors pain and recovery after outpatient surgery. It may help manage pain more safely and improve your comfort after you go home.
Nîmes, GardAges 18 years+ - NCT07164677Recruiting
Nerve block for pain after open-heart surgery
This study tests a nerve block (an injection near the back muscles) to see if it helps control pain after open-heart surgery. It might be a good option if you are having planned heart surgery through a cut in the middle of your chest.
SamsunAges 18–80 - NCT07310953Recruiting
Using new pain scales to guide rescue pain medicine after surgery
This trial tests if a simple pain scale (the NVS and PFAS) can help doctors better decide when to give extra pain medicine after surgery. It may help control pain more quickly and effectively after a procedure called VATS.
VigoAges 18 years+
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Common questions
- Are there clinical trials for post operative pain, acute?
- Yes. Clin2 currently lists 41 recruiting post operative pain, acute studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a post operative pain, acute trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a post operative pain, acute trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.