Clin2
NCT07229768Possibly a fitRecruiting

Study of 177Lu-CTR-FAPI for advanced solid tumors

Pancreatic Cancer

Part of Cancer, Digestive system, Hormones & metabolism clinical trials.

This trial tests a radioactive drug called 177Lu-CTR-FAPI for people with advanced solid tumors that have not responded to standard treatments. It targets tumors that show a specific protein (FAP) on PET scans. The study focuses on certain cancers like pancreatic, breast, and soft tissue sarcoma.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
4 people
Ages
18 years to 85 years
Study type
Interventional

Who can take part

  • You have an advanced solid tumor that has spread or cannot be removed, and standard treatments have not worked or are not available.
  • You are 18 or older.
  • You are in good physical condition (ECOG score 0 or 1).
  • A special PET scan shows your tumor has the FAP protein.
  • You have at least one tumor that can be measured on scans.
  • Your blood, liver, and kidney function are within acceptable ranges.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06553846Not yet recruiting· Phase 1
Targeted radiation therapy for advanced solid tumors

This trial tests a new radioactive drug, Lutetium-177 FAP-75, for people with advanced solid tumors that have not responded to standard treatments. The drug is designed to target and deliver radiation directly to cancer cells, potentially slowing tumor growth.

Shanghai, Shanghai Municipality
NCT07014254Not yet recruiting
Lu-177 CTR-FAPI for advanced digestive cancers

This trial tests a new radioactive drug that targets a protein called FAP on cancer cells. It is for people with advanced stomach, pancreas, colon, bile duct, or esophageal cancers that have spread and show high FAP levels on a special scan.

Xi'an, Shaanxi
NCT07135128Recruiting· Phase 1
Study of a radioactive drug for advanced solid tumors

This trial tests a new radioactive drug (225Ac-FAPI-XT) for people with advanced solid tumors that have stopped responding to standard treatments. It targets a protein called FAP found on many cancer cells, which may help deliver radiation directly to the tumor.

Jinan, Shandong
NCT06640413Recruiting· Phase 1
Study of radioactive treatment for FAP-positive advanced tumors

This trial tests a new radioactive treatment (177Lu-OncoFAP-23) alone or combined with an immunotherapy (L19-IL2) for people with advanced solid tumors that have a specific protein called FAP. It's for patients whose cancer has grown despite standard therapies.

Bergamo, Bergamo
NCT06197139Recruiting· Phase 1
Study of a new targeted radiation therapy for advanced solid tumors

This trial tests an investigational drug called [177Lu]Lu-XT117, which delivers a small dose of radiation directly to cancer cells that have a specific protein called FAP. It is for people with advanced solid tumors who have run out of standard treatment options or cannot tolerate them.

Guangzhou
NCT06211647Recruiting· Phase 1
177Lu XT117 for advanced solid tumors

This trial tests a new radioactive drug, [177Lu]Lu-XT117, that seeks out and delivers radiation to solid tumors that have a specific marker called FAP. It's for people whose cancer has not responded to other treatments or who have no other options.

Beijing

Hear when a new Pancreatic cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.