Bacterial therapy for diarrhea-type irritable bowel syndrome
Part of Digestive system clinical trials.
This trial tests a new treatment made from gut bacteria for people with irritable bowel syndrome that causes diarrhea (IBS-D). The treatment may help restore healthy gut bacteria and reduce symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have been diagnosed with IBS-D using standard criteria (Rome IV).
- You have a sign of unhealthy gut bacteria, like abnormal bile acid levels or a positive breath test.
- You have a normal C-reactive protein level and your gallbladder is still in place.
- You are willing to use birth control during the treatment period and for one week after.
- You can safely undergo antibiotics, an endoscopy, and a colonoscopy with bowel prep.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests three treatments for diarrhea-predominant irritable bowel syndrome (IBS-D): brain stimulation (TMS), medication, or probiotics. It aims to find which approach works best to reduce pain and improve bowel symptoms.
This trial tests whether putting stool (fecal microbiota) from a donor into your bowel can improve symptoms in people with IBS who are not IBS-C. It may help by changing the gut bacteria that can influence IBS symptoms.
This trial tests a new treatment called SMT04 for people with irritable bowel syndrome (IBS), specifically the diarrhea or mixed types. It may help reduce symptoms like abdominal pain and changes in bowel habits.
This trial tests a new treatment called CMTS0929 for people with inflammatory bowel disease (IBD), a condition that causes inflammation in the digestive tract. It aims to see if the treatment works and is safe.
This study tests whether a synbiotic (a mix of good bacteria and fiber) can improve symptoms of irritable bowel syndrome (IBS), especially for people with diarrhea-predominant or mixed type IBS, or functional diarrhea.
This trial studies fecal microbiota transplantation, which is transferring stool bacteria from a healthy donor to help rebalance gut microbes. If you have irritable bowel syndrome (IBS) that hasn’t improved after several standard treatments, this study may see whether it reduces your symptoms and is safe.
Hear when a new Diarrhea trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.