Clinical trials
Diarrhea clinical trials
Below are recruiting diarrhea clinical trials, each written for real people, not researchers. We’re tracking 73 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07285785RecruitingPhase 4
Rifaximin for children with acute diarrhea
This study tests whether a medicine called rifaximin, taken along with oral rehydration solution, helps children aged 6 to 11 recover faster from acute (short-lasting) diarrhea that is likely caused by a bacterial infection. The study compares rifaximin plus oral rehydration versus oral rehydration alone.
Lynwood, CaliforniaAges 6–12 - NCT06960369RecruitingPhase 1
Brain stimulation and probiotics for diarrhea-predominant IBS
This trial tests whether combining a type of brain stimulation (repetitive transcranial magnetic stimulation) with a probiotic tablet can help people with diarrhea-predominant irritable bowel syndrome. It aims to improve symptoms by targeting both the brain and the gut.
Suzhou, JiangsuAges 18–70 - NCT07000383Recruiting
Gelsectan for diarrhea-predominant IBS
This trial tests if Gelsectan, a dietary supplement, can safely reduce diarrhea and abdominal pain in people with diarrhea-predominant irritable bowel syndrome (IBS-D). It may be a new option for managing your symptoms.
Ho Chi Minh City, District 5Ages 18 years+ - NCT07264998Recruiting
Gut bacteria study in breast cancer patients on Abemaciclib
This study looks at how gut bacteria changes in people taking Abemaciclib (a breast cancer drug) and whether that relates to diarrhea. It may help find ways to prevent or manage this side effect.
Wuhan, HubeiAges 18–75 - NCT07581756Recruiting
Brain Stimulation Treatment for Diarrhea-Prone Irritable Bowel Syndrome
This trial tests whether repeated magnetic stimulation applied to the scalp (a non-invasive procedure) can reduce diarrhea and belly pain in people with diarrhea-predominant IBS. The goal is to see if this brain-based treatment can improve your symptoms.
Suzhou, JiangsuAges 18–70 - NCT06337695RecruitingPhase 2/Phase 3
Preventing immunotherapy-related diarrhea in advanced cancer
This study tests whether vedolizumab, a drug that reduces gut inflammation, can prevent diarrhea caused by immunotherapy (a type of cancer treatment). It is for adults with advanced melanoma, lung, or kidney cancer who have a stool marker of inflammation early in treatment.
Calgary, AlbertaAges 18 years+ - NCT07767370RecruitingEarly Phase 1
Two experimental drugs for chronic inflammatory diarrhea
This study tests two experimental capsules, ND-12 and H-6, given together to adults with long-term diarrhea caused by inflammation in the gut, such as active ulcerative colitis. It aims to see if the combination is safe and helps reduce diarrhea and inflammation.
Nanjing, JiangsuAges 18–75 - NCT06612411RecruitingEarly Phase 1
Testing a probiotic for diarrhea-predominant IBS
This trial tests whether a specific probiotic (Bacillus subtilis) can help relieve symptoms in people with diarrhea-predominant irritable bowel syndrome (IBS). The study also looks at whether the probiotic works by increasing a natural chemical called hypoxanthine in the body.
NanjingAges 16–80 - NCT06444633Recruiting
Home delivery of diarrhea treatment for children under 5
This trial tests whether sending ORS (oral rehydration solution) and zinc tablets to homes ahead of time helps treat diarrhea in young children faster. It's for caregivers in Nigeria who speak English or Hausa and have a child under 5.
AbujaAges 15 years+ - NCT05677282RecruitingPhase 4
Single-dose antibiotics for sudden watery diarrhea
This trial compares rifaximin or azithromycin (both antibiotics) taken as a single dose, with loperamide to control symptoms. It’s for people with recent, watery diarrhea who can be treated and followed as an outpatient, to see which option works better and is safer.
DjiboutiAges 18–60 - NCT07309315Recruiting
Testing a bacteria pill to prevent diarrhea from chemotherapy
This trial tests if a pill made from a harmless bacteria can prevent diarrhea caused by certain chemotherapy treatments. It is for people with advanced colorectal cancer or breast cancer who are about to start specific treatments.
Shenzhen, GuangdongAges 18 years+ - NCT06839209Recruiting
Add-on TOXCLEAN for recurrent C. difficile diarrhea
This trial tests an add-on treatment called TOXCLEAN for people with repeat C. difficile diarrhea. It aims to see if adding TOXCLEAN to standard antibiotics helps more than antibiotics alone.
RomaAges 18 years+ - NCT06982703Enrolling by invitation
Butyrate for antibiotic-related diarrhea
This trial tests if a supplement called butyrate can prevent or reduce diarrhea caused by antibiotics. If you're starting antibiotics, you may be able to join.
PadovaAges 18–80 - NCT06737666RecruitingPhase 1
Tong-Xie-Yao-Fang for Diarrhea-Predominant IBS
This trial tests an herbal formula called Tong-Xie-Yao-Fang for people with diarrhea-predominant irritable bowel syndrome (IBS-D). It aims to see if the treatment helps symptoms and how it works. Healthy volunteers are also needed for comparison.
Beijing, Beijing MunicipalityAges 18–70 - NCT06356545Recruiting
Study of children with chronic diarrhea in China
This study looks at children with ongoing diarrhea to better understand the causes and find better ways to diagnose and treat it. It will use advanced testing to learn more about the condition.
Shanghai, Shanghai MunicipalityAges 1 month–3 years - NCT07264985Recruiting
Gut bacteria and diarrhea in breast cancer patients on pyrotinib
This study looks at how gut bacteria relate to diarrhea in breast cancer patients who are taking a drug called pyrotinib. By understanding this link, doctors hope to better manage side effects in the future.
Wuhan, HubeiAges 18–75 - NCT04038619RecruitingPhase 1
Fecal transplant for immune-therapy diarrhea or bowel inflammation
This early-phase study tests whether stool/fecal microbiota transplant (a fecal transplant) can help people who develop significant diarrhea or colitis after immune-checkpoint therapy. It aims to reduce bowel inflammation and improve symptoms, while carefully checking for infections.
Houston, TexasAges 18 years+ - NCT04528303Recruiting
Genetic testing comparison for long-lasting childhood diarrhea
This study compares two types of genetic tests—whole genome sequencing and whole exome sequencing—to find causes of long-lasting diarrhea in children. It may help doctors diagnose the reason for diarrhea faster, which can guide treatment.
Shanghai, Shanghai MunicipalityAges Up to 6 years - NCT05519254RecruitingPhase 3
Lactoferrin and lysozyme for lasting diarrhea in young children
This trial tests whether a supplement (lactoferrin and lysozyme) can help children who have long-term effects after diarrhea. It’s designed for children ages 6 to 24 months and checks whether improving gut recovery can reduce ongoing problems.
Homa BayAges 6 months–2 years - NCT05766826Recruiting
Coupons to help pregnant women get safer water
This study gives pregnant women coupons to support safer water access. It aims to see whether this kind of help improves water safety during pregnancy.
KisumuAges Any age - NCT06206707Recruiting
FMT for Diarrhea and Colitis After Immunotherapy
This trial tests whether a treatment called fecal microbiota transplant (FMT) — transferring healthy gut bacteria — can help relieve diarrhea and colitis caused by immunotherapy drugs. If you have melanoma or kidney cancer and are experiencing diarrhea after immunotherapy, this study may offer a new option.
Aarhus NAges 18 years+ - NCT06237452RecruitingPhase 3
VE303 to prevent repeat C. diff infections
This trial tests a new medicine called VE303, a live bacterial therapy, to prevent C. diff infections from coming back. It is for people who have had C. diff at least once in the last 6 months, or who are at high risk for a repeat infection due to age or other health problems.
Huntsville, AlabamaAges 12 years+ - NCT06684470RecruitingEarly Phase 1
Combining a low-FODMAP diet with medication for IBS-D
This trial tests if a special diet (low-FODMAP) combined with a medication (mirtazapine) can improve IBS with diarrhea symptoms. It is for adults who have not tried these treatments before.
Jacksonville, FloridaAges 18–70 - NCT07545759RecruitingPhase 2
Testing brenipatide for IBS with diarrhea symptoms
This study tests whether a new medication called brenipatide can help people with IBS-diarrhea (IBS-D) reduce belly pain and loose stools. IBS-D is a condition where the intestines move too quickly, causing frequent diarrhea and discomfort.
Mesa, ArizonaAges 18–75
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Diarrhea trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for diarrhea?
- Yes. Clin2 currently lists 73 recruiting diarrhea studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a diarrhea trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a diarrhea trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.