Treating IBS-D with brain stimulation, drugs, or probiotics
Part of Digestive system clinical trials.
This trial tests three treatments for diarrhea-predominant irritable bowel syndrome (IBS-D): brain stimulation (TMS), medication, or probiotics. It aims to find which approach works best to reduce pain and improve bowel symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have been diagnosed with irritable bowel syndrome (IBS) using the Rome IV criteria.
- Your stools are mostly loose or watery (Bristol types 6 or 7) and rarely hard or lumpy.
- You have had loose stools on at least 4 days and moderate to severe belly pain over a 2-week period.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if a type of brain stimulation called low-frequency repetitive transcranial magnetic stimulation (lf-rTMS) can reduce belly pain in people with irritable bowel syndrome that causes diarrhea (IBS-D). It is a non-invasive treatment that uses magnetic pulses to target areas of the brain involved in pain perception.
This trial tests a new treatment made from gut bacteria for people with irritable bowel syndrome that causes diarrhea (IBS-D). The treatment may help restore healthy gut bacteria and reduce symptoms.
This trial tests if a special diet (low-FODMAP) combined with a medication (mirtazapine) can improve IBS with diarrhea symptoms. It is for adults who have not tried these treatments before.
This trial tests whether combining a type of brain stimulation (repetitive transcranial magnetic stimulation) with a probiotic tablet can help people with diarrhea-predominant irritable bowel syndrome. It aims to improve symptoms by targeting both the brain and the gut.
This trial tests whether repeated magnetic stimulation applied to the scalp (a non-invasive procedure) can reduce diarrhea and belly pain in people with diarrhea-predominant IBS. The goal is to see if this brain-based treatment can improve your symptoms.
This study uses brain stimulation (TMS) customized for each person to treat IBS. It uses MRI scans to see how the brain responds, aiming to find better ways to predict who will benefit from this therapy.
Hear when a new IBS (Irritable Bowel Syndrome) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.