Clin2
NCT07245095Worth exploringRecruiting

Pre-medication for better views during upper endoscopy

EsophagogastroduodenoscopySimethiconeN-AcetylcysteinePremedicationVisualizationEsophagogastroduodensocopy (EGD) ProcedurePlacebo - ControlGastritis Associated With Helicobacter Pylori

Part of Cancer, Digestive system clinical trials.

This trial tests whether taking two medicines (N-acetylcysteine and simethicone) before an upper endoscopy helps the doctor see the stomach lining more clearly. It may be an option for people having their first endoscopy, without active bleeding.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
132 people
Ages
18 years to 99 years
Study type
Interventional

Who can take part

  • You are between 18 and 70 years old.
  • You do not have active bleeding in your stomach or intestines.
  • You are not allergic to N-acetylcysteine or simethicone.
  • You have never had an upper endoscopy before.
  • You have not had stomach or weight-loss surgery.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06729307Not yet recruiting· Phase 4
Combining ondansetron and dyclonine for a more comfortable upper endoscopy

This study tests whether two medicines—ondansetron (to reduce nausea) and dyclonine (to numb the throat)—can make an unsedated upper endoscopy more comfortable. If you are having this procedure, the combination may help you feel less gagging and nausea.

NCT06713421Recruiting
Pronase to improve stomach cleanliness during endoscopy

This study tests whether a medicine called pronase, taken before an upper endoscopy (a scope test to look at your stomach), helps keep the stomach lining cleaner so the doctor can see better. If you are having a routine upper endoscopy, this might help make the exam more accurate.

Shanghai
NCT07271303Not yet recruiting
Study of a stomach-relaxing medication before painless upper endoscopy

This trial tests a medication (hyoscine butylbromide capsule) given before a painless upper endoscopy (a tube with a camera to examine your esophagus and stomach) to see if it helps relax the stomach and reduce discomfort during the procedure. Doctors will compare the medication to a placebo (a pill with no active medicine) to check if it is safe and effective.

NCT07293234Not yet recruiting
Does simethicone improve H. pylori detection during endoscopy? (SIMETHP)

This study tests whether giving a common anti-gas medicine (simethicone) before a routine endoscopy helps doctors find H. pylori bacteria more easily. If you are already being tested for H. pylori, this study might improve the accuracy of your test.

NCT07674160Not yet recruiting
Anti-gas medicine during water-assisted colonoscopy

This study tests whether taking an anti-gas medicine (simethicone) during a water-assisted colonoscopy helps clean the colon better so the doctor can see more clearly. If you're having a colonoscopy, you might be in this study to see if it improves your exam.

NCT06919120Not yet recruiting· Phase 4
Comparing ways to take simethicone for clearer colonoscopy

This study tests two different ways of taking simethicone (a medicine that reduces gas bubbles) before a colonoscopy to see which one gives doctors a clearer view. If the view is clearer, the doctor can find problems more easily, and you may need less preparation or fewer repeats.

Yiwu, Zhejiang

Hear when a new Premedication trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.