Does simethicone improve H. pylori detection during endoscopy? (SIMETHP)
Part of Digestive system clinical trials.
This study tests whether giving a common anti-gas medicine (simethicone) before a routine endoscopy helps doctors find H. pylori bacteria more easily. If you are already being tested for H. pylori, this study might improve the accuracy of your test.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 80 years old.
- You must have a positive H. pylori test from a stomach biopsy or similar procedure.
- You cannot have taken antibiotics or bismuth medicines in the last 4 weeks.
- You cannot have taken acid-suppressing drugs called proton pump inhibitors (like omeprazole) in the last 2 weeks.
- You cannot have taken H2 blockers (like ranitidine or famotidine) in the last 3 days.
- You must not have had major stomach surgery, be on blood thinners, have low platelets, be pregnant, or have serious health conditions that make sedation unsafe.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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