Clinical trials
Premedication clinical trials
Below are recruiting premedication clinical trials, each written for real people, not researchers. We’re tracking 22 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07410078Recruiting
Comparing medicines given before surgery for children
This trial compares different medicines given by mouth before surgery to see which works best to help children relax and have less pain. If your child is having day surgery, this study might help find the best pre-surgery medicine for them.
AnkaraAges 4–12 - NCT07245095RecruitingPhase 2
Pre-medication for better views during upper endoscopy
This trial tests whether taking two medicines (N-acetylcysteine and simethicone) before an upper endoscopy helps the doctor see the stomach lining more clearly. It may be an option for people having their first endoscopy, without active bleeding.
Mexicali, Estado de Baja CaliforniaAges 18–99 - NCT06671743RecruitingPhase 3
Medication before root canal to reduce pain
This study tests whether taking a medication before a root canal can reduce pain afterward. It is for people who need a root canal on a lower back tooth that has a painful, inflamed nerve but no infection at the root tip.
AjmanAges 20–50 - NCT07050095Recruiting
Virtual reality vs. medication for anxiety before eye surgery
This trial compares using a virtual reality headset against a standard anti-anxiety medication (midazolam) to help patients relax before dacryocystorhinostomy (tear duct) surgery. It aims to find a non-drug way to reduce anxiety.
CairoAges 18–65 - NCT07450456Recruiting
Can virtual reality reduce the need for pre-surgery calming medication?
This trial tests if using a virtual reality headset can help you feel calm before surgery, instead of or in addition to taking medication. You may qualify if you are having planned surgery and you want anxiety relief before the procedure.
Lugano, Canton TicinoAges 18 years+ - NCT05136976RecruitingPhase 3
Rituximab for anti-MAG neuropathy in specific patients
This Phase 3 study tests rituximab, an antibody medicine, for people with a particular type of nerve damage called anti-MAG–related demyelinating polyneuropathy. It aims to see if rituximab improves symptoms or function in patients who are considered “good responders.”
BrestAges 18 years+ - NCT06489327Recruiting
Melatonin before surgery for children
This trial tests two different doses of oral melatonin (a natural sleep hormone) given to children before surgery to help them relax. It may help your child feel calmer before their procedure.
Cairo, Cairo GovernorateAges 4–10 - NCT07461376Recruiting
A trial comparing two sleep medicines for children before surgery
This study tests two oral medicines given before surgery to help children relax and lower the need for stronger painkillers after the operation. It is for children having surgeries like hernia repair, circumcision, or hypospadias correction.
Cairo, Giza GovernorateAges 3–12 - NCT05681572RecruitingPhase 3
Sedation before surgery to help kids feel better after anesthesia
This study tests whether giving a calming medicine before general anesthesia improves how children feel and experience anesthesia afterward. The goal is to see which pre-surgery approach works best and is comfortable for kids.
Montpellier, MontpellierAges 7–18 - NCT03625011RecruitingPhase 4
Gabapentin before tonsil surgery to reduce pain
This trial tests whether giving gabapentin before pediatric tonsil (and possibly adenoid) removal can reduce postoperative pain. It may help children feel more comfortable after surgery while still being safe to use in the right patients.
Atlanta, GeorgiaAges 3–18 - NCT03735563RecruitingPhase 4
Less invasive surfactant timing with different pre-medications
This study tests whether giving a pre-medication before a less invasive lung treatment (surfactant) improves breathing in premature babies. It may help some babies avoid more invasive ventilation while still getting the lung medication they need.
OuluAges Any age - NCT04914234RecruitingPhase 4
Atenolol vs metoprolol for low blood pressure during nasal surgery
This trial compares two commonly used blood-pressure medicines—atenolol and metoprolol—to see which one works best for keeping blood pressure safely low during nasal surgeries. It may help patients have more stable anesthesia while reducing side effects from blood pressure changes.
Damanhūr, El-BeheiraAges 21–50 - NCT05260320Recruiting
Testing the best anesthesia plan for teens having jaw surgery
This study looks at whether a standardized anesthesia plan works best for kids and teens having Le Fort jaw surgery at Johns Hopkins. If you qualify, the team may use or adjust anesthesia to improve safety and comfort during surgery.
Baltimore, MarylandAges 14 years+ - NCT05876117Recruiting
Pre-medication to help claustrophobic patients complete MRI
This trial tests whether a pre-medicine approach can help people with claustrophobia successfully complete an MRI scan. It may help you avoid having to stop early due to anxiety or panic in the scanner.
Surrey, British ColumbiaAges 20–99 - NCT06080100RecruitingEarly Phase 1
Xenon sedation for stress relief before eye surgery
This study tests whether a calming gas called xenon can help reduce stress and anxiety before a specific type of laser eye surgery (SMILE). It may help people who feel very nervous or anxious before their procedure.
KrasnodarAges 18–45 - NCT06118710RecruitingPhase 4
Can we skip dexamethasone before paclitaxel?
This study tests whether it is safe to skip the steroid (dexamethasone) that is normally given before paclitaxel chemotherapy. If you are about to start paclitaxel for a solid tumor, this trial may help reduce side effects from premedication.
Rotterdam, South HollandAges 18 years+ - NCT06713421Recruiting
Pronase to improve stomach cleanliness during endoscopy
This study tests whether a medicine called pronase, taken before an upper endoscopy (a scope test to look at your stomach), helps keep the stomach lining cleaner so the doctor can see better. If you are having a routine upper endoscopy, this might help make the exam more accurate.
ShanghaiAges 18–70 - NCT06933550Recruiting
Study on collecting patient information in the emergency department
This study asks patients in the emergency department to answer simple questions about their symptoms and health. The goal is to collect information that can help doctors provide better care during the patient's visit.
GrazAges 18 years+ - NCT07036367RecruitingPhase 4
Melatonin before cataract surgery for older adults
This trial is testing whether a melatonin tablet placed under the tongue before surgery can help older adults feel calmer and more comfortable during cataract surgery. Melatonin is a natural sleep hormone that may reduce anxiety without the side effects of common sedatives.
Cairo, EgyptAges 60 years+ - NCT07101445RecruitingPhase 4
Comparing steroids to prevent reactions to motixafortide in multiple myeloma
This trial tests two different steroid medicines (methylprednisolone and dexamethasone) to see which works better at preventing side effects from motixafortide, a drug used to help collect stem cells for a stem cell transplant in people with multiple myeloma.
Atlanta, GeorgiaAges 18 years+ - NCT07565116Recruiting
Numbing Nose Spray vs. Calming Liquid Before Pediatric Surgery
This trial compares two safe, common ways to help children relax before surgery: a medicine sprayed in the nose versus a medicine given by mouth. The goal is to see which one works better and is easier for kids.
Diyarbakır, Outside of the USAges 2–10 - NCT04130022Enrolling by invitation
Ultrasound before anesthesia to reduce stomach risks
This trial studies using an ultrasound scan of the stomach before general anesthesia in children having planned (elective) surgery. The goal is to better understand stomach fullness and improve safety around anesthesia.
Columbus, OhioAges birth–18 years
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Common questions
- Are there clinical trials for premedication?
- Yes. Clin2 currently lists 22 recruiting premedication studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a premedication trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a premedication trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.