Comparing two drugs for cannabis-related nausea in the ER
Treatments studied
Part of Mental health clinical trials.
This trial tests whether haloperidol or olanzapine works better to stop severe nausea and vomiting caused by heavy cannabis use. If you use cannabis nearly daily and have had episodes of vomiting that come and go, this study may help find the best treatment for you.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have used cannabis (by smoking or vaping) almost every day for at least 6 months
- You have either been told before that you have cannabinoid hyperemesis, or have had 3 or more episodes of severe vomiting in the last 2 years that started and stopped and were separated by more than a month, or your doctor thinks this condition is the likely cause
- You are not pregnant or breastfeeding
- You do not take daily benzodiazepines (like Xanax or Valium), certain heart medications, or antipsychotics
- You do not have Parkinson's disease or a known allergy to haloperidol or olanzapine
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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