Lidocaine vs ketamine for hard-to-treat face pain
Part of Pain clinical trials.
This trial compares two medications, lidocaine and ketamine, given through an IV to see which is safer and works better for people with long-lasting face or mouth pain that hasn't improved with other treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have ongoing face or mouth pain that hasn't gotten better with other treatments or procedures
- You have been diagnosed with one of these conditions: trigeminal neuralgia, TMJ dysfunction, malignant otitis externa, migraine, or atypical facial pain
- You do not have serious heart problems or high blood pressure that is not controlled
- You are not allergic to lidocaine or ketamine
- You are not pregnant, breastfeeding, or have a history of substance abuse
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if a non-invasive brain stimulation technique (called TMS or tDCS) can help reduce long-lasting pain in the face, jaw, or mouth. It's for people who have tried other treatments without enough relief.
This trial tests whether giving a numbing medicine (lidocaine) into a small artery in the face (the external carotid artery) can help people with hard-to-treat chronic migraines or persistent face/skull pain. It is for those who haven't found relief from standard treatments.
This trial tests if adding lidocaine and ketamine to your current pain medicines can better control severe cancer-related pain that opioids alone haven't helped.
This trial tests if a combination of ketamine and lidocaine given through an IV can help people with constant, hard-to-treat migraines. It aims to find a new relief option for those who haven't improved with other treatments.
This trial tests if a liquid form of ketamine works as well as a common opioid (oxycodone) for treating pain in the emergency department. If you have arm, leg, back, or neck pain that isn't controlled by first treatments, you may be able to join.
This trial compares two pain-relief medicines (lidocaine vs. ketamine) given through an IV during open colorectal surgery. It aims to find which one works better to reduce pain after surgery.
Hear when a new Orofacial Pain trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.