Clin2
NCT07251829Possibly a fitNot yet recruiting

Embolization before radiation for enlarged prostate with cancer

Prostate Adenocarcinoma

Part of Cancer, Kidney & urinary clinical trials.

This study tests a procedure called prostate artery embolization (PAE) before radiation therapy for prostate cancer. The goal is to shrink the prostate and reduce urinary symptoms, which may improve the effectiveness of radiation and your quality of life.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
35 people
Ages
Any age
Study type
Interventional

Who can take part

  • You have been diagnosed with prostate cancer and are scheduled to have radiation therapy to the prostate.
  • Your prostate is enlarged, at least 50 cubic centimeters (about the size of a large walnut).
  • You have moderate to severe urinary symptoms, with an IPSS score of 15 or higher (your doctor can explain).
  • If you are taking hormone therapy or a 5-alpha reductase inhibitor (a medication for enlarged prostate), you must have been on it for at least 12 weeks and still meet the prostate size and symptom criteria.
  • You must not have had previous prostate surgery (like TURP or laser) or have a urinary catheter, nerve problems affecting your bladder, or a current or frequent urinary tract infections.
  • You must not be taking certain medications (like beta blockers or antihistamines) unless you have been on a stable dose for 6 months with stable bladder symptoms.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07364071Recruiting· Phase 2
Hormone therapy and targeted radiation for high-risk prostate cancer

This trial tests whether combining standard hormone therapy and radiation with a special targeted radiation (PSMA-targeted radiotherapy) is safe and effective for men with high-risk prostate cancer that hasn't spread outside the pelvis.

La Jolla, California
NCT07255508Not yet recruiting
Prostate artery embolization for enlarged prostate

This trial tests a new way to block blood flow to the prostate to shrink it and improve urinary symptoms. It uses a special gel called SquidPERI during a standard procedure called prostate artery embolization (PAE).

Marseille
NCT07293585Recruiting· Phase 3
Precision radiation to protect erectile function in prostate cancer

This trial tests a new radiation technique to better protect erectile function during prostate cancer treatment. It uses advanced imaging to precisely target the tumor while reducing harm to nearby structures.

Los Angeles, California
NCT04084938Recruiting
Clot-blocking treatment versus surgery for enlarged prostate

This trial compares artery embolization (blocking blood flow to the prostate) with standard surgery for urinary symptoms caused by an enlarged prostate. It may help patients who have moderate-to-severe bladder outlet symptoms and are looking for a treatment option when medicine didn’t work (or they don’t want medicine).

Oslo
NCT07477626Recruiting· Phase 3
Radiation therapy after prostate surgery for advanced prostate cancer

This study tests whether radiation therapy to the pelvis after prostate removal helps men whose cancer was found in nearby lymph nodes. The goal is to prevent cancer from coming back and improve survival.

Dongguan, Guangdong
NCT05707468Not yet recruiting
Radiation and hormone therapy before surgery for prostate cancer that has spread to a few spots

This trial tests a new approach using radiation therapy (radiotherapy) combined with hormone therapy before the standard surgery to remove the prostate. It aims to see if this combination can better control prostate cancer that has spread to a few spots (oligometastatic) and improve outcomes.

Guangzhou, Guangdong

Hear when a new Prostate Adenocarcinoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.