Comparing two surgeries for hiatal hernia and stubborn GERD
Part of Digestive system clinical trials.
This trial compares two surgical approaches (a 'partial wrap' and a 'full wrap' of the stomach around the esophagus) to fix a hiatal hernia and treat severe, hard-to-control reflux (GERD). It may be a good option if your reflux hasn't improved with medication and you have a hiatal hernia.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 85 years old.
- You have a hiatal hernia (a stomach bulge into the chest) that has been seen on both a CT scan and a scope test (gastroscopy).
- You have GERD that doesn't get better after taking strong acid-reducing pills (like omeprazole 40 mg) daily for 2–3 months.
- Your GERD has been confirmed by either a 24-hour acid test or an endoscopy showing esophagitis (inflammation).
- You do NOT have a condition that affects how your esophagus moves, and you have never had surgery on your esophagus or upper belly area.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
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This study compares two keyhole surgery methods to fix a hiatus hernia in children and teenagers. The goal is to see which one works better at controlling reflux and healing the esophagus, using a camera test to check results.
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This trial tests if surgically closing a small hiatal defect helps reduce acid reflux (GERD) symptoms. It is for people who are surgical candidates and have confirmed acid exposure on testing.
This study compares two common weight-loss surgeries (gastric bypass and sleeve gastrectomy) to see which is better at treating acid reflux in people with obesity. If you have reflux and are considering surgery, this trial will randomly put you in one of the two surgery groups.
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