Comparing two surgeries for hiatal hernia and stubborn GERD
Part of Digestive system clinical trials.
This trial compares two surgical approaches (a 'partial wrap' and a 'full wrap' of the stomach around the esophagus) to fix a hiatal hernia and treat severe, hard-to-control reflux (GERD). It may be a good option if your reflux hasn't improved with medication and you have a hiatal hernia.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 85 years old.
- You have a hiatal hernia (a stomach bulge into the chest) that has been seen on both a CT scan and a scope test (gastroscopy).
- You have GERD that doesn't get better after taking strong acid-reducing pills (like omeprazole 40 mg) daily for 2–3 months.
- Your GERD has been confirmed by either a 24-hour acid test or an endoscopy showing esophagitis (inflammation).
- You do NOT have a condition that affects how your esophagus moves, and you have never had surgery on your esophagus or upper belly area.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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