Closing the hiatal gap for GERD relief
Part of Digestive system clinical trials.
This trial tests if surgically closing a small hiatal defect helps reduce acid reflux (GERD) symptoms. It is for people who are surgical candidates and have confirmed acid exposure on testing.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 50 years old
- You have a hiatal opening smaller than 4 cm (about 1.6 inches)
- Your body mass index (BMI) is under 30
- A pH test shows your esophagus has acid for more than 5.5% of a 24-hour period
- You are healthy enough for surgery and not pregnant, a prisoner, or a child
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a more precise way to place a small probe during reflux testing in women and people with lower body weight, which may improve accuracy and comfort. It compares different probe positions to see which works best for these patients.
This trial studies a way to guide laparoscopic surgery for a paraesophageal (hiatal) hernia using special measurements during the operation (FLIP) and an endoscopy check. It may help doctors choose the most appropriate surgical wrap to better control reflux after surgery.
This trial is testing a device called RefluxStop™ that is implanted during keyhole surgery to treat acid reflux (GERD). The study will check how safe and effective the device is for people with long-term GERD, and it aims to help reduce heartburn and other reflux symptoms.
This trial compares two surgical approaches (a 'partial wrap' and a 'full wrap' of the stomach around the esophagus) to fix a hiatal hernia and treat severe, hard-to-control reflux (GERD). It may be a good option if your reflux hasn't improved with medication and you have a hiatal hernia.
This trial tests a new endoscopic procedure called anti-reflux mucosal ablation therapy to reduce acid reflux in people who still have symptoms despite taking acid-reducing medication. The goal is to see if this treatment helps improve heartburn and related symptoms.
This study tests a new endoscopic procedure to help people with severe acid reflux that hasn't improved with strong medications. The procedure tightens the valve between the stomach and esophagus to reduce acid backing up.
Hear when a new Gastro Esophageal Reflux trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.